Female | 40
Is My Elevated Immature Granulocytes Level Cause for Concern?
Systematic increases in immature granulocytes Good morning, Firstly, I will mention that I suffer from numerous chronic inflammatory diseases, as this may be relevant. These include Ulcerative Proctitis; Atrophic Gastritis; Last year, I also underwent two cervical electrosurgery procedures due to advanced dysplasia (CIN3). (The last colposcopy and colonoscopy did not reveal any suspicious changes) For a year now, my blood morphology tests have been showing an elevated level of immature granulocytes: The latest test (May '24) showed: Immature granulocytes IG - 0.09 thousand/µl; Norm: 0-0.04 thousand/µl Immature granulocytes IG % - 1.00; Norm: 0-0.5% The rest of the blood morphology is normal, leukocytes in urine - within the norm. Previous results (April '23): Immature granulocytes IG - 0.05 thousand/µl; Norm: 0-0.04 thousand/µl Immature granulocytes IG % - 0.7; Norm: 0-0.5% (and a very slightly elevated MCV) Even older (January '23): Immature granulocytes IG - 0.04 thousand/µl; Norm: 0-0.04 thousand/µl Immature granulocytes IG % - 0.6; Norm: 0-0.5% (and a very slightly elevated MCV and basophils) There is a clear upward trend since last year. I initially thought this was due to extreme stress (CIN3, LLETZ etc). Now I am not so sure... Are these results very concerning and indicative of a cancerous process? Can chronic inflammatory states cause an increase in IG, or is it rather some kind of “acute” disease state? Could the fact that I rode a bike to the laboratory (medium and short-term physical effort) affect the increase in results? I would be very grateful for your response and advice. Best regards, J.
General Physician
Answered on 23rd May '24
Raised levels of these are often linked to chronic inflammation similar to stress, in this case, it is important to control them initially. With the status of attempted diagnosis for specific inflammatory conditions, your previous experience, and the new procedures on the lookout for anything new, don't hesitate to let a doctor know. It would be helpful to get solid advice from your healthcare provider concerning your test results.
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