Why is Bone Marrow Transplant required?

It is done when the bone marrow is unable to or not healthy enough to produce healthy cells and perform its functions due to chronic infections, disease or cancer treatments. Know More

What is the process you should follow to get Bone Marrow Transplant in India?

From the initial diagnosis to the recovery and departure it takes a long duration. Also it is a daunting task to prepare to stay for a long period of time in a foreign country. There are many government and personal steps you will have to follow to get here. Know More

Who can be a donor for a bone marrow transplant?

The Donor will have to travel with the patient to meet with the medical team. Here the donor will have to undergo several tests and evaluations done before it could be determined if they are the best candidate for donation. Know More

What are the risks and complications involved in Bone Marrow Transplant?

There are many risks and complications involved in bone marrow transplant process.These risks can surface both during and after the bone marrow transplant is complete. Know More

- Last updated : Jan 17th, 2020

What is the Bone Marrow Transplant Cost In India?

The bone marrow transplant cost in India ranges from ₹15,00,000 ($21,013) to ₹ 40,00,000 ($55,800). It depends on which BMT you are recommended. Autologous and allogeneic are the most common types of bone marrow transplants used to treat blood cancers and disorders.

Here is an estimated bone marrow transplant cost in India by types:

Types of BMT	BMT Cost In India (INR and Dollar)
Autologous Bone marrow transplant	₹15,00,000 - ₹17,00,000 ($21,013-$23,652)
Allogeneic Bone marrow transplant	₹25,00,000 - ₹30,00,000 ($35,022-$42,027)
Haplo-Allogeneic Bone marrow transplant	₹35,00,000 - ₹40,00,000 ($49,031-$56,036)

*To be on the safer side be prepared for 5% to 10% variation on the estimated cost depending on your condition. These charges include hospital stay for a specific period, surgeon’s fees, operation theatre charges, anesthesia charges and meals for the patient and one companion.

You must be wondering why cost for bone marrow transplant differs in different types of transplant? Here are the factors which will tell you the reason why:

Your condition : Depending on the type of cancer or disorder you have you’ll be recommended a type of transplant.
Age : Age of the patient is also a factor that affects the overall bone marrow transplant cost. Treatment cost is higher for patients under 20 or pediatric patient. This is because their care and total stay in the hospital is usually higher.
The type of transplant : As we know there are three types of transplant. Following are the different types of bone marrow transplants:
1. Autologous Bone marrow transplant:
2. Allogeneic Bone marrow transplant:
3. Haplo-Allogeneic (Haploidentical) Bone marrow transplant:

Bone Marrow Transplant Cost In India (Autologous,Allogeneic,Haplo-Allogeneic)

Here are some of the most common questions people ask while seeking bone marrow transplants in India:

Bone marrow transplant cost in India with comparison to other countries:

Countries	Average cost
USA	₹2,47,36,250 - ₹ 5,65,40,000 ($350,000- $800,000)
United Kingdom	₹1,64,89,184 - ₹4,12,22,960 ($233,310- $583,275)
Germany	₹70,67,500 - ₹1,76,68,750 ($100,000-$250,000)
Turkey	₹35,33,679 - ₹70,67,500 ($49,999-$100,000)
India	₹15,00,000 – ₹40,00,000 ($21,013-$56,036)

The reasons for variations in costs between India and other developed countries are:

Currency : Basically the Indian currency is lower than the USD, pounds, euro, etc. So obviously everything is cost effective here. Be it your stay, medical treatment or consultation, everything will cost you far lesser when compared to other countries.
Standard of living : Standard of living is quite low in India than the other developed countries such as USA. So the prices of facilities be it in the field of transport, overall stay, food and medical treatment are cost-effective.
Competition : There are many Bone marrow transplant center in India, so you have wider choice according to your budget of hospitals of your choosing. Since all of them have the BMT related technology and specialists with cost effective treatment.
Hospitals : Many hospitals in India, be it government or private, offer bone marrow transplant facilities. So, you have a wider option to choose by comparing the bone marrow transplant costs in India, as the prices may vary among them.
Doctor : Basically, here in India the doctors charge less compared to doctors in the other developed countries. This is one of the major reasons for the cost-effective bone marrow transplant price in India. However, the charges of doctor may vary according to their popularity, experience and the hospitals where they practice.

There are few other factors why getting bone marrow transplant in India is a good option.

Even though there is a huge difference in the amount compared to developed countries it does not mean Indian hospitals compromise in their quality.

What could be the additional costs in BMT?

If you’re thinking of bone marrow transplant cost in India or anywhere else in the world be prepared to shell out money for post and pre- transplant facilities.

First we want to discuss all the costs that come under pre-bone marrow transplant stage:

Following is a complete guide of not only all the necessary steps you will have to take before the bone marrow transplant but also discusses the costs you will incur during this stage:

Pre bone marrow transplant cost:

Pre - procedure tests and treatments	Cost Estimation
Health checkup	Physical examination and health check up with your doctor might cost around ₹600 ($8) - ₹5000($70)
All investigations	There are a number of investigations which will be required like a blood test, PFTs and RVG for the heart, Electrocardiogram (ECG), Chest and Dental X-ray, etc which will set you back by around ₹55,892 ($800) to ₹69,865 ($1000)
HLA typing (if required)	HLA typing is only required in case of an allogeneic/haploidentical transplant which costs around ₹80,000 ($1,112.53) additionally.
Chemotherapy	Cost of chemotherapy is approximately ₹1,04,797 ($1500) to ₹1,25,077 ($1800) per chemo cycle. You may also have to pay for Induction chemotherapy that will cost you approximately ₹1,38,974 ($2000) to ₹2,08,462 ($3000) .
Radiation Therapy/ Radiotherapy	A rough estimate of the cost for Radiation treatment based on the procedure or technique can range between ₹1,66,770 ($2400) to ₹4,86,955 ($7000) depending on the package.
Donor fees (if required)	In case of allogeneic transplant, there are number of tests and expenses related to extraction of stem cells. This is more expensive in a haploidentical transplant.
Medication	Medication prescribed for your recovery.
Pre - operations cost	Pre-operations cost, medication costs, documentation costs etc.

What costs come under the Post-bone marrow Transplant stage?

In case of any problems, unanticipated monitoring, extended stay etc. requirements will be charged separately. This is not included in the transplant cost and hence it comes under post-transplant stage, that is:

Post bone marrow transplant cost:

Monitoring and requirements
Medications cost	There will be many expensive medicines prescribed to you after the transplant.
Any additional service availed	Any extended hospital stay and use of services
Other consultation	Any other consultation with your doctor and other consultations.
Complications management and unanticipated care	The cost for monitoring and treatment for complications management and unanticipated care is separate from the transplant cost. If for any reason you have stay beyond the stipulated period, you will be charged separately.
Follow - up costs	After the transplant, you will have to follow up with your doctor regularly for your health check up.

For your information the following videos will help make you understand everything involved the transplant procedure:

Autologous Bone marrow transplant procedure

Allogeneic Bone marrow transplant procedure

Why you should get bone marrow transplant in India?

You will find some of the internationally accredited BMT centers in India.
Here in India the BMT doctors are extremely trained and experienced.
Not only are they highly experienced but have also have participated and led various cancer and BMT centered research in countries like USA, UK, Canada, etc.
The technology and infrastructure required for BMT is on par with the developed countries

FAQ:

Is there a difference between bone marrow and stem cells?
It’s just that the bone marrow is the semi-solid sponge like tissues present in the center of most bones, primarily found in the ribs, vertebrae, breastbone, and hip bones. This is where the hematopoietic stem cells are ultimately produced.
It includes stem cells that form blood cells like white blood cells, red blood cells and platelets. And these cells are ultimately used for the bone marrow transplant.

Why is BMT done?
Bone marrow transplant is a last resort treatment and it is required when the bone marrow of the patient is unable to or is not healthy enough to produce healthy cells or perform its functions and this happens due to chronic infections, disease, cancer which effects the bone marrow and cancer treatments.

How is the donor's marrow matched to the patient's marrow in allogeneic transplantation?
To increase success rate of the transplantation and to decrease complications, it is important that the donor’s bone marrow matches as closely as possible to the receiver (patient). For this you will have to undergo the HLA type test to find out the compatibility. The success of transplantation in case allogeneic BMT depends largely on how closely the HLA antigen of the donor matches to that of the patient.
For an allogeneic transplant siblings are most preferable candidates as they more likely to match the patient compared to an unrelated donor. However, the chance of sibling being an exact match donor is only around 25%. Finding the exact match HLA donor using an unrelated donor is very low. However nowadays doctors do haploidentical bone marrow transplant which also has a good success rate.

What is HLA testing?
The sets of proteins that people have on the surface of their cells called human leukocyte- associated antigens (HLA), it differs in different people.

What are the possible immediate side effects of BMT?
While there are many risks following bone marrow transplant the immediate side effects are as follows:.
And Following are some of the direct side effects that you might experience after receiving bone marrow transplant:
• Mouth Sores
• Nausea and vomiting
• Fatigue
• Low platelets levels, which might decrease effective blood clot
• Low levels of red blood cells, which can cause anemia
• Diarrhea
• GVHD or HVGD (Graft vs host disease OR host vs Graft disease)
If you’re undergoing autologous stem cells, in rare cases you may also experience:
• Shortness of breath
• Chest pain or tightness
• Urine may appear red in colour

What are the side-effects of chemotherapy and radiation?
As you will receive chemotherapy and radiation before the bone marrow transplant to kill all the cancer cells, you might experience some side effects which are as follows:
• Fatigue
• Hair loss
• Skin problems
• Swelling of the brain (increased intracranial pressure)
• Seizures
• Earaches or difficulty hearing if the ear is in the treatment area
• Easy bruising and bleeding
• Infection
• Anemia (low red blood cell counts)
• Nausea and vomiting
• Appetite changes
• Constipation
• Diarrhea
• Mouth, tongue, and throat sores and pain while swallowing
• Nerve and muscle numbness, tingling, and pain
• Dry skin and nail col our changes
• Urine and bladder changes and kidney problems
• Weight loss
• Mood changes

How is bone marrow harvested for a transplant?
This applies in cases of both autologous and allogeneic.
A needle is inserted into the rear pelvic bone (hip bone) where the largest amount of bone marrow is located, from here the bone marrow will be extracted using a syringe.
Several punctures are made through skin and bone to extract sufficient bone marrow. This does not require any surgical incisions so be rest assured there will be only skin punctures where the needle was inserted.
A sterile bandage is applied to the site when the collection ends.

Usually one to two quarts of marrow/stem cells are harvested.

How does bone marrow transplant help a patient?
Bone marrow transplant procedure is used to replace damaged and diseased bone marrow. Apart from this, it is also used to restore a new immune system that will help fight the existing or remaining cancer cells which have not been killed through chemotherapy and radiation.

What Are the Significant Risks of a Transplant?
There are many risks and complications involved in bone marrow transplant process. These risks can surface both during and after the bone marrow transplant is complete. The complications on vary depending on the health of the patient, the stage of cancer, doctor’s diagnosis, requirement and the type of bone marrow transplant.
1. Graft-versus-host disease-GVHD
2. Lung Damage
3. Bone problems
4. Infections
5. Cataracts
6. Infertility
7. Risk of developing new cancers
8. Death

What happens after bone marrow is transplanted?
After the transplant engraftment takes place. During this process the transplanted cells enter the bloodstream and travel to the bone marrow, where they reproduce new white blood cells, red blood cells, and platelets .
This process takes about 2 to 4 weeks. During this period, you will be kept in an extremely sterilized unit used especially for BMT patients called ‘Hepa-filtered units’ and will be constantly monitored. On regular basis you will undergo various tests and you blood count will be checked."
Complete recovery of patients as well as the immune function of the stem cells takes about 1 to 2 years for those who are receiving allogeneic or haplo-allogeneic transplant.
Doctors will conduct regular evaluations to confirm that new blood cells are being produced and that the cancer has not returned.
The doctor might also perform Bone marrow aspiration (the removal of a small sample of bone marrow through a needle for examination under a microscope) to determine how well the new marrow is working.

Is the process for an autologous transplant different from allogeneic?
In an autologous transplant the doctors will initially harvest your own bone marrow/stem cells that are relatively cancer free. This bone marrow will be freezed and be re-transplanted once the treatments are over.
The harvested marrow is often treated before transplantation with anticancer drugs in order to get rid of cancer cells in a process called “purging”. This is to minimize chances of the cancer coming back.

Why is BMT so Costly?
Bone marrow transplant is an extremely complicated procedure. There are various measures taken to make sure that the transplant won’t create long lasting complications.
In order to do that they take help of machines and units custom created for a BMT transplant patients that are called ‘hepa-filtered units’. The purpose of such units is to maintain an extremely sterilized environment for the patients whose immunity is at its lowest since the infections fighting cells are just recovering.
Additionally, the equipments like apheresis machine, laboratory use, etc. are also taken into consideration when deciding the cost of bone marrow transplant.

Why is haplo-allogeneic (Haploidentical) transplant more expensive than allogeneic transplant?
In both Haplo-identical and an allogeneic transplant a donor‘s marrow is used for the transplant. The major difference is that in haploallogenic the donor is a partial HLA match to the patient’s HLA. There are various complications that could occur, such as GVHD (Graft versus host disease) in case of a haploallogenic transplant. So to prevent any future problems there are many tests done and observations are made before the transplant can be approved.

What could be the consultation costs?
Consultation fees of a bone marrow transplant specialist, which includes physical examination and health check up with your doctor, might cost around ₹600 ($8) - ₹5000($70).

For how long will you have to continue with the medication?
There is a follow-up period of about 1 year after the discharge following the transplant and the monitor period. The medications might go on for many years following the treatment depending on the consulting oncologist’s observations and orders.

Ask your question below, our experts will reply to you:

Questions & Answers (19)

Verified User (posted anonymously)

22nd January, 2020 at 10:25 am

My daughter is suffering from Leukaemia doctor said it will get cured completely by stem cell transplant will she get cured

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Pankaj

22nd January, 2020 at 09:42 am

What are the types of cancer that are treated effectively using Bone marrow transplant?

Dr. Babita Goel replied

22nd January, 2020 at 01:23 pm

The Food and Drug Administration (FDA) has approved CAR T-cell therapy to treat two types of blood cancers: acute lymphoblastic leukemia (ALL), and diffuse large B-cell lymphoma. If you could be more specific about the disease, then we will be in better position to solve your queries. Consult an oncologist, who on evaluating the patient will guide you through the treatment and answer all your queries. Hope our answer helps you.

Verified User (posted anonymously)

24th December, 2019 at 05:59 pm

Son diagnosed AML with FLT3 possitive

Dr. Babita Goel replied

25th December, 2019 at 10:33 am

The FLT3 gene helps regulate cell survival and reproduction. The gene mutation causes immature blood cells to multiply uncontrollably. Therefore, people with the FLT3 mutation have a more severe form of AML. The chances of relapse is common in these cases after treatment. The prognosis is poor. You need to consult a hematologist to decide upon the line of treatment. This type of AML has to be treated aggressively. There are newer treatment regimes to treatment these cases along with the regular treatment. But a hematologist is in a best position to evaluate and discuss the entire details for your better understanding. Regular follow up with doctor,councelling to deal with the stress due to disease to patient and family is very important ,prevention from infections, get vaccinated, some light physical activity will be of help. Consult a hematologist. Hope our answer helps you.

Verified User (posted anonymously)

14th December, 2019 at 12:04 am

My mother has CML.She was diagnosed in 2012.Now it is in Blast phase.She is being treated in Paras hospital Patna.Here doctor says she needs BMT.Could you tell me which is the hospital best suited to our needs and the also the doctors..

Team ClinicSpots replied

25th December, 2019 at 11:54 am

Hello, Below, we have listed down some of the best hospitals for BMT in India: -Gleneagles Global Hospital, Chennai -Nanavati Hospital, Mumbai -S l Raheja, Mahim -All India Institute of Medical Sciences (AIIMS), New Delhi Also, we have listed down some of the best hospitals for bone marrow transplant in India: -Dr Deenadayalan M Experience: 17+ Years Gleneagles Global Hospital, Chennai -Dr. Narendra Agrawal Experience: 18+ years Rajiv Gandhi Cancer Institute & Research Centre, Delhi -Dr. Lalit Kumar Experience: 37+ years All India Institute of Medical Sciences (AIIMS), New Delhi Hope our answer helps you.

Verified User (posted anonymously)

1st November, 2019 at 09:08 am

My sister is suffering from AML she is in Prince Aly Khan hospital under doctor Tapan Sakia she might have to go for BMT she is 27 years old my father is retiredrnrnCan you tell me the full cost including pre and post BMT cost of following hospitalsrnrn1Jaslok rn2 kokilabenrn3 Rahejarn4 breach candyrn

Team ClinicSpots replied

25th December, 2019 at 11:43 am

Hello, As we are unable to quote you for Bone marrow transplant in different hospitals, we would like to letyou know that the general cost range that private hospitals in India range is between Rs. 15,00,000 ($20,929) to Rs. 40,00,000 ($55,816). Hope our answer helps you.

Verified User (posted anonymously)

30th October, 2019 at 03:48 am

My brother 56 years old has been diagnosed with BPDCN a month ago

Team ClinicSpots replied

8th November, 2019 at 10:44 am

Hello, BPDCN is a rare disease of the bone marrow and blood that affects multiple organs, including the lymph nodes and the skin. Tagraxofusp-erzs (ElzonrisTM) is approved for the treatment of BPDCN. Sometimes treatment includes therapies that are used for AML, acute lymphoblastic leukaemia (ALL) or lymphoma. The length for which a patient responds to these treatments is usually not very long. After a relapse, second remissions difficult to achieve. Allogeneic hematopoietic stem cell transplant (allo-HCT), especially if offered in the first remission, may result in longer remissions. The current recommendation for BPDCN patients is to be evaluated for an allo-HCT and to begin searching for a donor. Consult a haematologist for further guidance or about the line of treatment. Hope our answer helps you.

Verified User (posted anonymously)

14th October, 2019 at 09:22 am

I am suffering from acute lymphoblastic lekuemia if I want bone marrow transplant any government facilities that help me in concession fees

Team ClinicSpots replied

15th October, 2019 at 05:39 pm

Hello, Some medical cards provided by the government for concession on medical treatments are: Ayushman bharat, CHGS, etc but most of them only apply to government employees. Some government and charitable hospitals that might provide treatment to under-privileged patients from all over India with concessions are: 1. Christian Medical College(CMC) and Hospital, Vellore 2. All India Institute of Medical Sciences (AIIMS), New Delhi 3. Rajiv Gandhi Cancer Institute & Research Centre, Delhi 4. Tata memorial , Mumbai 5. Basavatarakam Indo American Cancer Hospital and Research Institute, Hyderabad 6. Kidwai Memorial Institute of Oncology, Bangalore I hope our answer helps

Verified User (posted anonymously)

9th October, 2019 at 02:35 am

Imunity Defenses problem Giving IVIG 4 injection every month of Reliance Co

Dr. Babita Goel replied

7th December, 2019 at 04:40 pm

As per my understanding you are being administered Intravenous Immunoglobulin ( IVIG) 4 injection every month. IVIG is used to treat various conditions like autoimmune, infectious, idiopathic diseases and others. In your case you have not specified the disease. Consult an oncologist he will asses clinical condition of the patient his disease and guide you. Hope our answer helps you.

Verified User (posted anonymously)

11th September, 2019 at 07:14 am

I want to know that cost of blood cancer treatment I mean bone marrow transplant

Team ClinicSpots replied

12th December, 2019 at 05:00 pm

Hello, Normally, the bone marrow transplant cost in India ranges from Rs. 15,00,000 ($20,929) to Rs. 40,00,000 ($55,816). Note: The cost may vary depending on the experience of the doctor and also from one hospital to the other. Hope our answer helps you.

Verified User (posted anonymously)

27th August, 2019 at 09:11 am

My 4yr son was detected with Beta Thalassemia Major on 26-06-2019, during routine check up and doctor asked for haemoglobin check up since his body was not growing as per peers. We had done 3 blood transfusion till date. He is having 12/12 match with his mother. We live in Surat, Gujarat. We request you to suggest best success ratio hospitals with approx cost and no of bone marrow transplants done in last year.

Team ClinicSpots replied

27th August, 2019 at 05:09 pm

Hello, I would suggest you to visit Hospitals in Mumbai for a Bone marrow transplant as Hospitals here have a better infrastructure to support and conduct complex procedure such as this. Also specialists that have vast experience and knowledge in this procedure. We don’t have last year’s BMT success records of hospitals, one can only tell an individual’s success ratio depending on the patient’s condition and the case. Following are the best Hospitals in Mumbai for bone marrow transplant are: 1. S l Raheja, Mahim 2. Nanavati Hospital, Mumbai 3. Jaslok Hospital, Mumbai He will require an allogeneic Bone marrow transplant which ranges from around ₹25,00,000 to ₹30,00,000 at all private hospitals which might vary case to case. Hope our answer helps

Verified User (posted anonymously)

16th August, 2019 at 02:20 am

Need medical opinion in my brother case history. As described as bone marrow transplant in initial stage from B.hospital.

Team ClinicSpots replied

16th November, 2019 at 09:39 am

Hello Vivek, We would suggest you consult a bone marrow transplant surgeon for the medical opinion in the case of your brother. Here we have mentioned some of the best bone marrow transplant surgeons in India: 1. Dr. Suresh Advani MBBS, DM – Oncology 46 years of experience Medical Oncologist S L Raheja Fortis Hospital, Mahim, Mumbai Monday, Wednesday, Friday 06:30 PM – 08:00 PM 2. Dr. Ashok Kumar Vaid MBBS, MD – Internal Medicine, DM – Oncology 31 years of experience Medical Oncologist Medanta – The Medicity, Gurgaon Sector 38, Gurgaon Monday, Tuesday, Thursday – Saturday 09:30 AM – 02:00 PM; Wednesday 09:30 AM – 01:00 PM 3. Dr. Amit Rauthan MBBS, MD – General Medicine, DM – Oncology 19 years of experience Medical Oncologist Manipal Hospital, Old Airport Road, Bangalore Monday, Tuesday, Thursday- Saturday 02:00 PM – 05:00 PM Hope our answer helps you.

Verified User (posted anonymously)

3rd August, 2019 at 11:54 pm

My daughter suffering with this disease Sickle cell anemia, Please suggest.. Where I need to consult for free treatment.

Dr. Babita Goel replied

9th December, 2019 at 10:33 am

Bone marrow transplant also called stem cell transplant, is potential cure for sickle cell anemia. Treatment options are medications to reduce pain and prevent complications Vaccinations to prevent infections, and blood transfusions.Life style changes are also ofhelp like Take folic acid supplements daily, and choose a healthy diet. Drink plenty of water Avoid temperature extremes. Basically, there are some hospitals where concession on medical treatments are available though cards like Ayushman bharat, CHGS, etc. Some government hospitals are : 1. Tata Memorial Hospital, Mumbai 2. All India Institute of Medical Sciences, New Delhi 3. Christian Medical College (CMC) and Hospital, Vellore Consult a hematologist. Hope our answer helps you.

Yashika bansal

1st August, 2019 at 10:35 pm

My daughter age 9 yrs is suffering from B Lymphoblastic leukemia

Click here to view your answer

Verified User (posted anonymously)

2nd July, 2019 at 02:31 pm

My son was diagnosed for wiskott aldric syndrome and Doctors have advised born marrow TRANSPLANT which can be done at specialist hospitals in India please we need you to avail us the cost of bone marrow transplant in hospital. also inform i can take any benefits governent card like, ayushman card, bal sandarbh card any other inform.

Dr. Babita Goel replied

9th December, 2019 at 10:26 am

Wiskott–Aldrich syndrome (WAS) is a very rare X-linked recessive disease characterized by eczema, thrombocytopenia (low platelet count), immune deficiency, and bloody diarrhea (due to thrombocytopenia). It needs a multidciplanary approach. Treatment too has to cover different aspects of the syndrome. Transplantation is the current accepted treatment HLA typing of all potential donors should be done. If a family donor is not identified, an unrelated donor should be searched so that potential donor is available.But over all benefits of the therapy has to be taken into consideration. Usually, the bone marrow transplant cost in ranges from Rs. 15,00,000 ($20,929) to Rs. 40,00,000 ($55,816). The cost may vary depending on the experience of the doctor and also from one hospital to another. Consult a hematologist. Hope our answer helps you.

Verified User (posted anonymously)

29th May, 2019 at 10:56 am

Kya HIV patient ka bone marrow transplant ho sakta h

Team ClinicSpots replied

8th June, 2019 at 01:32 pm

Hello, Assuming you’re a HIV positive with cancer in need of Bone Marrow Transplant, we will first have to check your reports. We will have to see the diagnosis, medical reports, medical history, etc, to see whether a Bone Marrow Transplant would be necessary or not. There are ways to control HIV like increasing the CD34 count. Apart from this there are also other ways but only after that can you be considered a transplant. Now, Considering you are seeking cure for HIV through Bone marrow transplant (BMT) . There have only been two successful cases where HIV was cured with Bone marrow transplant and in both cases the patients had cancer with BMT as a last resort treatment. In case of both cases the patients were suffering from life-threatening advanced stage cancer. The first such case occurred in Berlin, where an American Patient named Timothy Brown had myeloid leukaemia and was also HIV positive. He was in the advanced stage of this blood cancer and the doctors had decided to do a Bone marrow transplant and also attempt to clear the HIV simultaneously. Since HIV patients can only get an allogeneic transplant, they had searched for a donor with a rare genetic mutation of the CCR5 gene for both the Berlin patient to make them HIV-resistant. After that the Berlin patient took regular bantiretroviral drugs that suppress HIV and has been virus-free ever since The second successful case was in London, where the patient with Hodgkin’s lymphoma and HIV virus was also in the advanced stage of cancer as the doctors decided attempted a stem cell transplant for their cancer and simultaneously attempt to clear HIV. And similarly they searched a stem cell donor with a rare genetic mutation of the CCR5 gene for the patient to make them HIV-resistant. The London patient stopped taking the medication 18 months ago and there is no sign of a return of HIV. They are not likely to do BMT just to cure HIV. But if you are a cancer patient you should consult a hemato-oncologist for added information. I hope our answer helps

Oladapo bolaji

27th April, 2019 at 03:18 pm

My sister was diagnosed for Leukemia and Doctors have advised she seeks cure STEM TRANSPLANT which can be done at specialist hospitals in India please we need you to avail us the cost of bone marrow transplant in your hospital

Team ClinicSpots replied

28th April, 2019 at 08:51 pm

Hello Oladapo , Since Acute Myeloid leukaemia, Acute lymphoblastic leukaemia and even Chronic myeloid leukemia usually require an allogeneic bone marrow transplant. She will have to find an HLA match donor for the stem cell transplant. And then send all the tests, medical reports and HLA results so the oncologist here can confirm the prognosis. Siblings are the best candidate for stem cell donation in this case. So the cost of an allogeneic stem cell transplant in India is around ₹25,00,000($35,022) - ₹30,00,000 ($42,027). In case she requires an autologous stem cell transplant, it will cost around ₹15,00,000 ($21,013) - ₹17,00,000 ($23,652). Following are some of the best hematologists with many years of experience and practicing in the best hospitals in India that provide stem cell transplantation: 1. Dr. Suresh Advani Experience: 45+ years S.L.Raheja Fortis Hospital, Mumbai 2. Dr. Sameer A. Tulpule Experience: 16+ years Kokilaben Dhirubhai Ambani Hospital & Medical Research Institute, Mumbai 3. Dr. Maheboob Basade Experience: 24+ Years Jaslok Hospital, Mumbai 4. Dr. Uma Dangi Experience: 13+ Years Fortis mulund 5. Dr. Narendra Agrawal Experience: 18+ years Rajiv Gandhi Cancer Institute & Research Centre, Delhi 6. Dr. Shishir Seth Experience: 13+ years Apollo Indraprashtha Hospital, Delhi 7. Dr. Satish Kumar A Experience: 19+ years Columbia Asia Referral Hospital, Bangalore 8. Dr Deenadayalan M Experience: 17+ Years Gleneagles Global Hospital, Chennai 9. Dr. Mangesh Kamath Experience: 12+ Years BGS Gleneagles Global Hospitals, Bangalore 10. Dr. Lalit Kumar Experience: 37+ years All India Institute of Medical Sciences (AIIMS), New Delhi Hope our answer helps

Verified User (posted anonymously)

4th April, 2019 at 11:02 am

i m 42 years old woman and I am diagnosed with AML. Beofre they saud i had severe anemia and gave some medicines but after some tests showed my blood count was low they and decided I have leukemia and I need a bone marrow transplant. I have a brother I match for the donor and I want to come to india because we heard hospitals there are good and cost is less. What do you think?"

Team ClinicSpots replied

10th April, 2019 at 05:56 pm

Hello, An allogeneic transplant for a person suffering from acute myeloid leukemia (AML) is standard. If you have already tested with a sibling and they are HLA match to you then you can easily get bone marrow transplant in India. India does have one of the most cost effective options for an allogeneic transplant. You can send your health reports and the HLA match test to us on our whatsapp so we can guide you more efficiently on, Following are some of the best multi-specialty hospitals that have well-equipped BMT units and experienced staff for the same: 1. Jaslok Hospital, Mumbai 2. S.L.Raheja Fortis Hospital, Mumbai 3. Kokilaben Dhirubhai Ambani Hospital & Medical Research Institute, Mumbai 4. Medanta - The Medicity, Gurgaon 5. Gleneagles Global Hospital, Chennai 6. BGS Gleneagles Global Hospitals, Bangalore 7. All India Institute of Medical Sciences (AIIMS), New Delhi 8. Rajiv Gandhi Cancer Institute & Research Centre, Delhi I hope our answer helps

Verified User (posted anonymously)

16th February, 2019 at 09:55 am

my abbu suffering PTLD from last 4 months his immune system is still very weak what should we do now i have spent a lot money while transplant please help me out

Team ClinicSpots replied

21st February, 2019 at 12:01 pm

This is a form of complication that occurs after the transplant and can be contained if detected early. There are various forms of treatments depends on the type of PTLD. Since you have discovered this complication your father can get the treatment. Now the treatments depend on the type of PTLD he has and there are various options. The treatment includes antibody therapy with the medication doctor will provide for this treatment (rituximab is the most known one), he might also require chemotherapy or in some cases maybe even radiation, etc. It is necessary you visit your BMT specialist or team or visit good hospital to get this under control. Some hospitals that I would recommend to you for this purpose are: 1. Public/charitable hospitals with great BMT records around India. Though they might has longer waitlist: a. Tata Memorial Hospital, Mumbai b. Christian Medical College and Hospital, Vellore c. All India Institute of Medical Sciences (AIIMS), New Delhi 2. Private Hospitals with fast service but higher cost of treatment due to high class facilities: a. S.L.Raheja Fortis Hospital, Mumbai b. Apollo Hospital, Chennai c. Columbia Asia Referral Hospital, Bangalore d. Medanta - The Medicity, Gurgaon

Verified User (posted anonymously)

16th February, 2019 at 07:11 am

hey experts can you please tell me what is graft-versus-host disease?

Team ClinicSpots replied

19th February, 2019 at 09:13 am

In an allogeneic transplant, the patient’s stem cells are replaced with healthy stem cells from a donor. In some cases GVHD occurs when the foreign stem cells don’t recognize the recipient’s body and attack it. And vice-versa in the Host-versus-graft disease, the recipient’s stem cells attack the new donated cells because perceiving it as a foreign body. This is a complication that varies from mild to serious, and in serious cases the whole transplant might fail and may prove fatal to the patient. If detected early there is a high chance of maintaining it and avoiding further health pronlems. Hence it is very important for the transplant patient to be aware of any changes in their body even after the transplant

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