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  3. Why Some Patients Deteriorate Rapidly in Hospital
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Why Some Patients Deteriorate Rapidly in Hospital

By Dr. Smriti Vajpeyi| Last Updated at: 27th Aug '26| 16 Min Read

Overview

Hospitalization is intended to provide patients with expert care and close monitoring, but some patients can experience unexpected or rapid deterioration. This article explores the factors that may contribute to worsening health during a hospital stay, including disrupted sleep and circadian rhythms, medication or treatment errors, advanced age, chronic conditions, and cultural or communication barriers. It also highlights initiatives such as Martha’s Rule and explains how patients and caregivers can stay involved by reporting changes, understanding medications and procedures, asking questions, and communicating concerns promptly.

Why Some Patients Deteriorate Rapidly in Hospital

When you or a loved one is ill, a hospital can seem reassuring and supportive. You feel confident that the medical expertise and experience of clinical practitioners will get things back on track. This underlying belief is why news of patient deterioration comes as a massive shock. 

Consider a 2024 study on in-hospital cardiac arrests, as published in Resuscitation Plus. It found that although clinically important deterioration was present in over 33% of cases, the early warning score system failed to trigger in almost 16% of these cases. Although this study relates to cardiac issues, the challenge may be prevalent across hospital settings.

The whole situation leaves you feeling unsettled. Did you make the wrong decision on seeking hospitalization? 

Let us understand why some patients seem to worsen much faster in hospitals. It will help you identify strategies to prevent and manage this deterioration.

Circadian Rhythm May Be Disrupted

Imagine being in a hospital room where the windows remain shut, the blinds drawn. Perpetually brightly lit. 

Time goes by, and the difference between night and day becomes blurred. This disrupts the body’s natural circadian rhythm and impacts sleep. It can also affect your mood, bringing on frustration and disillusionment.

An insightful 2024 study published in Sleep and Breathing found that several hospitalized respiratory patients experienced poorer sleep. They slept much better back home. They felt that this was due to operational interruptions and noise.

Sleep issues can impact a patient’s mental health and overall recovery curve. Mental health deterioration is closely linked to poorer physical health outcomes. This could also be why some studies note that exposure to nature can have a therapeutic effect on psychological metrics during an acute hospital admission. 

Medical Treatment Mistakes and Oversights

Unfortunate as it is, one cannot rule out the real possibility that medical mistakes also contribute to patient deterioration in hospitals. 

These errors could start with an oversight during a nursing handoff or an incorrectly administered medication. In serious cases, the results of these mistakes can be disastrous.

The probability of errors may rise in treating complex conditions, such as metastatic cancer. According to a 2026 German study published in PubMed, chemotherapy and antibody-based therapies are not free of prescription errors and inaccurate dosing. Or even inappropriate treatment regimens. 

Such errors can impact the effectiveness of these procedures, which are already associated with morbidity risk for patients. This scenario can also explain why a patient may deteriorate faster after treatment. (Yes, the treatment had shortcomings.)

Patient Age and Pre-existing Conditions Play a Part

The ways hospitalization impacts patients is not homogeneous, differing by patient age and other factors. For example, consider a senior adult. They have been battling a chronic condition, such as hypertension, for many years. It is understandable that they may fare worse than a younger individual with the same illness. 

Socio-cultural factors, surprisingly, may also affect the outcomes. This may be acutely felt in hospitalization related to mental health. A 2026 BMC Psychiatry study emphasized that patients with certain cultural or religious beliefs may be more uncomfortable in seeking mental health care. Refusing the required care will affect the prognosis.

Institutions providing healthcare education also acknowledge these factors and have started building their programs accordingly. As Wilkes University notes, professionals must deliver informed care with respect to cultural perspectives.

Many nursing courses, such as RN-MSN online programs, emphasize cultural understanding to deliver appropriate patient care. Professionals often pursue online courses to balance studies and work. It means they directly see the impact of cultural sensitivity in action.

This is largely reassuring for patients and their families. Practitioners will be able to understand their apprehensions and concerns and recommend the future plan accordingly.

Hospitals Are Taking Action. We Should Too.

The positive news is that this situation is not going unnoticed. Hospitals globally are taking action to avoid rapid patient deterioration by establishing more precise warning systems.

NHS England is making meaningful strides with Martha’s Rule, a patient safety initiative that considers the concerns of patients, caregivers, and staff. According to official programme data from 2024 to 2026, 72% of calls came from families and carers. But here’s the highlight: around 31% related to acute deterioration.

Besides improving detection systems, many hospitals are also amping up training for clinical staff. The goal is to bring greater vigilance and closer monitoring not only for patients in intensive care but also elsewhere.

Food needs to undergo improvement too, and at least awareness of this is rising. Unappetizing or over-processed food is unlikely to support recovery. 

As Kate Arnold,  a nutritionist, says in a 2026 feature on The Independent, “Food waste is astronomical in the NHS, but is it any wonder when, apart from food safety and calorie content, no thought goes into the quality of food? Decent food not only helps with morale but could help save the NHS money with speedier recoveries and faster patient turnarounds.” 

As a patient or caregiver, you can improve health outcomes through caution. It can help you monitor your response to treatment more carefully and prevent mistakes during handoffs and other procedures. Consulting an interdisciplinary team for complex conditions can provide you with a complete view of your ailment and recovery, highlighting areas of concern. 

Here is some essential guidance on staying alert during hospitalization.

What to watch for

What you can do

Changes in your conditionTell the healthcare team about new symptoms or a worsening of older ones.
MedicationsAsk what each medication is for. If you have any allergies, report them.
Tests and proceduresAsk what is being done and why it is needed. Confirm what the expected results are so you can notice deviation.
Getting in and out of bed independentlyAlways ask for support if you feel weak or unsteady. Don’t be in a rush to do everything by yourself.
CommunicationMake sure doctors and nurses know about vital symptoms and concerns.
DischargeBefore leaving, confirm which medicines you must take and when you must return for follow-up appointments. Collect your test results. Also, ask about warning signs you should watch out for.

Conclusion

Patient deterioration during hospitalization can result from a combination of illness severity, individual risk factors, treatment challenges, and environmental or communication issues. While hospitals continue to strengthen monitoring systems and patient-safety practices, patients and caregivers also have an important role to play. Staying informed, reporting changes quickly, asking questions about treatment, and maintaining clear communication with healthcare professionals can help identify potential problems sooner. When care and patient involvement work together, the chances of recognizing deterioration and supporting a safer recovery can improve.

FAQs

How can I lower my risk of falls in the hospital?
If you feel dizzy or unsteady, ask for assistance before trying to get out of bed. Keep frequently used items, such as your spectacles or wet wipes, within reach. It is best to follow the hospital team's mobility recommendations.

Which symptoms should I report to the doctor or nurse immediately?

Tell your healthcare team about sudden or worsening symptoms such as difficulty breathing or intense pain. Do you feel confused and dizzy? These signs also need to be looked into. As a broad rule, any major changes in your condition must be reported, even if you feel they are not important.

I am uncomfortable with my treatment plan. What should I do?

Don’t let your intuition go unheard. As a priority, discuss your concerns in detail with your healthcare team. Ask about the rationale behind the recommendation and its potential benefits. You should also explore if there are any alternatives you can pursue instead. Seeking another professional opinion may be appropriate if you feel unsure even after these discussions.

Care and Caution Must Coexist 

Hard as it is to admit, an extended hospital stay may have inherent risks for patients with severe health conditions. However, avoiding hospitalization may neither be possible nor advisable. As a patient or a caregiver, your best plan is to remain vigilant. Communicate with your caregivers regularly and update your team on any changes in your condition.

Unnerving as illness can be, it is imperative to remember that hospitals are the safest place you can be when trying to recover. Your healthcare team is there to help you recuperate, and your involvement in the process can allow them to do it better.

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