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10 Best Genetic Disorders doctors in Nerkundram

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Dr. C.thirupathi Genetic Disorders

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Dr. P. Selvaraj Genetic Disorders

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Dr. P.n.ramdoss Genetic Disorders

Dr. P.n.ramdoss

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21 years of experience

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Dr. D. Vijayasekaran Genetic Disorders

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Questions & Answers on "Genetic Disorders" (275)

Dear Doctor, Due to my father's high blood viscosity, suspicion of polycythemia arises, necessitating blood draws every 3 weeks to maintain appropriate levels. At 69 years old, he experiences symptoms such as skin itching, swelling, head numbness, and fatigue. Currently, his JAK2 V617F mutation showed 0.8 then 1.2%, with JAK2 exon 12 negative and EPO at 13.4. Abdominal CT and chest X-ray are normal. After a few months of phlebotomy, his levels normalized. Now, we await the bone marrow biopsy results, which do not confirm Polycythemia Vera: "Microscopic description: The bone marrow biopsy sample shows somewhat hypocellular hematopoietic parenchyma relative to age, which is terminally mature. Myeloid ratio is 2:1 with dominance of late precursors; no blast cells are noted. The number of megakaryocytes is normal with no clustering. There is no interstitial fibrosis or lymphoid infiltrate. Diagnosis: Mature, hypocellular hematopoietic parenchyma without myeloproliferative features. Cytogenetic analysis confirmed male karyotype; no clonal chromosomal abnormalities detected. Indication for examination D7510 Secondary polycythemia Note Submicroscopic rearrangements, small structural chromosomal aberrations, DNA-level differences cannot be ruled out with the method used." I am quite confused as JAK2 positivity typically suggests PV, yet the biopsy suggests otherwise, possibly indicating secondary polycythemia. Could you please clarify based on this information what you personally think is more likely, Polycythemia Vera or another secondary cause? Thank you very much for your help.

Male | 67

Your father's symptoms and test results do suggest some complexity. The presence of JAK2 mutation often points towards Polycythemia Vera (PV), but the bone marrow biopsy does not show typical myeloproliferative features, suggesting it might be secondary polycythemia instead. Consult a hematologist, specializing in blood disorders, and can provide a more accurate diagnosis and appropriate treatment plan.

 

Answered on 3rd July '24

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I think I am having hiv.. what can I do whether iam having hiv or not.

Male | 32

Common signs of HIV include unexplained weight loss, fatigue, fever, and swollen lymph nodes. The virus spreads mainly through unprotected sex and sharing needles. To address your worries, consider getting tested for HIV, as early detection is crucial for effective management. Consulting a hematologist can provide clarity and support tailored to your situation. They can guide you through testing, and if needed, discuss potential treatments. Remember, many people living with HIV lead healthy lives with proper care. 

Answered on 27th Jan '25

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Sickle cell anemia report bare main janna hai

Female | 16

Sickle ce­ll anemia is a health problem. Pe­ople with it have red blood ce­lls that are bent in a moon shape. The­ bent cells get stuck in tiny blood tube­s. This causes much hurt and low energy. It also le­ads to getting sick easily. Sickle ce­ll anemia happens because­ of a gene issue from parents. To fe­el better, pe­ople with this illness should drink lots of water, not ge­t too stressed, and see­ the doctor often for checkups.

Answered on 23rd May '24

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