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Sulfamethoxazole-trimethoprim also recognized as Bactrim is not usually used in treating chlamydia. This is because it is a bacteria that spreads through intimate contact. This may lead to painful urination, unusual discharge, and sometimes no signs at all. Normally, antibiotics such as azithromycin or doxycycline are used to cure chlamydia. If you suspect that you have the disease, it is important to get tested and treated so as to avoid any further complications.