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New treatment for Alzheimer 2023

By Ipshita Ghoshal| Last Updated at: 27th Mar '24| 16 Min Read

What is the most promising treatment for Alzheimer's in 2023?

The U.s food and drug administration has granted approval for a new Alzheimer's drug, Leqembi (lecanemab-irmb) . The new treatment for Alzheimer has been granted through the accelerated approval pathway. Leqembi is an Alzheimer's drug breakthrough. It  is the second medication in a new category that targets the underlying pathophysiology of Alzheimer's disease. This advancement is a crucial step forward in the ongoing battle to effectively treat this challenging condition. 

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Are you curious about the latest advancements in Alzheimer’s treatment drug? Read on!

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Are there any new drugs or medications for Alzheimer's in 2023?

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As of now, in 2023 Leqembi is the only new medicine for Alzheimer’s disease. In July 2023, the US Food and Drug Administration (FDA) granted full approval for Lecanemab as a new Alzheimer’s drug. This allows healthcare professionals to administer the drug to patients with early Alzheimer's in the USA under the name Leqembi. 
 

Remternetug is a new drug made by Eli Lilly for early-stage Alzheimer's. It's immunotherapy like Donanemab but with potential improvements. Unlike other immunotherapies, it's given through skin injections. It aims for better effectiveness and fewer side effects. This method is similar to insulin pens used for diabetes. 

Can lifestyle changes slow down Alzheimer's progression? Find out now!

Can lifestyle changes or interventions help slow down Alzheimer's progression in 2023?

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Some studies suggest that our diet can impact our brain's ability to think and remember as we age. The Mediterranean diet and the related MIND diet have shown cognitive benefits in studies. The diet includes elements to lower blood pressure. 

Researchers are actively studying these diets to determine if they can prevent or delay Alzheimer's disease. The Mediterranean diet focuses on fruits, vegetables, whole grains, fish, and healthy fats. These elements have shown promising evidence in supporting brain health. 

One study, based on older adults, revealed that eating leafy green vegetables daily may slow down age-related cognitive decline. It was also found that eating fish regularly is associated with high cognitive function. It also reduces the rate of cognitive decline with age. 

Hence studies are still going on to establish the facts that lifestyle changes can actually impact Alzeigmer’s progression. 

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Unveiling the potential side effects of new Alzheimer's treatments. Find out below!

What are the potential side effects of new Alzheimer's treatments?

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Like any medicine, Leqembi may have side effects. The most common ones are brain swelling and bleeding, which usually improve with time. Some people may experience headaches, confusion, dizziness, vision changes, nausea, and seizures. It happens as a result of swelling and bleeding. Other side effects include nausea, vomiting, and changes in blood pressure. 


How effective are the new treatments for Alzheimer's compared to existing ones?

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Before Leqembi’s approval, the full results from a final clinical trial called Clarity-AD were released. The trials indicated that the new Alzheimer’s drug was able to remove the amyloid and tau proteins from people’s brains who have early Alzheimer’s. 

Leqembi slowed the decline in thinking and memory skills by 27%. It improved their quality of life by up to 56%.

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Get the scoop on the clinical trials for new Alzheimer's treatments in 2023!

Are there any clinical trials for new Alzheimer's treatments in 2023?

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Yes, the approval of the new Alzheimer’s drug is based upon the results from the clinical study Clarity AD. The study was conducted on 856 patients who had early-stage Alzheimer’s disease. Before the study, it was made sure that the patients had the presence of harmful amyloid protein. This protein is known to potentially cause dementia. 

Phase 3 of the clinical trial study showed results that proved that the new Alzheimer’s drug has effective benefits. The data reported from phase 3 of this study led to the accelerated approval of Leqembi. 


What are the latest advancements in Alzheimer's treatment?

Leqembi is a new Alzheimer’s drug. It is meant to be given to patients who have mild Alzheimer’s. As compared to earlier medications Leqembi proved to be more effective in removing amyloid proteins. Hence, getting the accelerated approval. 


 

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Question and Answers

A year ago i was hospitalized for a week and was diagnosed with dyskinesia, I had involuntary leg and head movements, I had tics sometimes light headiness and palpitations. After seeing a neurologist I was diagnosed with peripheral vertigo..gave me diazepam but after a week I was told to stop it after I told my physician that I was not walking properly...I couldn't walk in a straight line and that's when she prescribed me a different medication cinnarizine and pyridoxine. Now a year after I find myself not getting better. I'm having difficulty breathing (occasionally), my legs are stiff and I'm having tremors on both of them and on my hands but the right hand and leg are worse, specific movement of the tongue makes me feel familiar symptoms and despite drinking medication I still feel dizzy sometimes especially at night, when I close my eyes or In a dark place. Sometimes I feel stiffness on my hips and start walking strangely, my entire body feels strange..like I get shivers. Sometimes I feel like bending my back outwards sometimes I feel like hugging my knees and staying in that position A month ago I had swelling on my head that I could not understand where it came from it wasn't painful it was itchy and sometimes gave me a headache, I always get red spots which are itchy on both my legs, now I constantly have difficulty breathing. I feel like despite taking the medication I was prescribed nothing is getting better but worse. It's been a year of taking medication and still I'm not getting better.

Female | 23

Answered on 30th May '25

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