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Questions & Answers on "Colour Doppler" (256)
Dear Doctor, Due to my father's high blood viscosity, suspicion of polycythemia arises, necessitating blood draws every 3 weeks to maintain appropriate levels. At 69 years old, he experiences symptoms such as skin itching, swelling, head numbness, and fatigue. Currently, his JAK2 V617F mutation showed 0.8 then 1.2%, with JAK2 exon 12 negative and EPO at 13.4. Abdominal CT and chest X-ray are normal. After a few months of phlebotomy, his levels normalized. Now, we await the bone marrow biopsy results, which do not confirm Polycythemia Vera: "Microscopic description: The bone marrow biopsy sample shows somewhat hypocellular hematopoietic parenchyma relative to age, which is terminally mature. Myeloid ratio is 2:1 with dominance of late precursors; no blast cells are noted. The number of megakaryocytes is normal with no clustering. There is no interstitial fibrosis or lymphoid infiltrate. Diagnosis: Mature, hypocellular hematopoietic parenchyma without myeloproliferative features. Cytogenetic analysis confirmed male karyotype; no clonal chromosomal abnormalities detected. Indication for examination D7510 Secondary polycythemia Note Submicroscopic rearrangements, small structural chromosomal aberrations, DNA-level differences cannot be ruled out with the method used." I am quite confused as JAK2 positivity typically suggests PV, yet the biopsy suggests otherwise, possibly indicating secondary polycythemia. Could you please clarify based on this information what you personally think is more likely, Polycythemia Vera or another secondary cause? Thank you very much for your help.
Male | 67
Your father's symptoms and test results do suggest some complexity. The presence of JAK2 mutation often points towards Polycythemia Vera (PV), but the bone marrow biopsy does not show typical myeloproliferative features, suggesting it might be secondary polycythemia instead. Consult a hematologist, specializing in blood disorders, and can provide a more accurate diagnosis and appropriate treatment plan.
Answered on 3rd July '24
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I am 38 years and married. In October, last year I went to donate blood but was told one of the test is positive for HIV. I was asked to retest after months. I did and it is still same inconclusive result. What should I do?
Male | 38
The fact that your test was inconclusive implies that it's still not clear if you are HIV positive or not. Regarding the symptoms of HIV, they are similar to fever, tiredness, and weight loss. More likely, bringing about can be unsafe sex or sharing needles. Therefore, you must see a doctor
Answered on 23rd May '24
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My mother is losing weight without any reason? Is it a sign of cancer?
Female | 37
While losing weight unexpectedly doesn't necessarily mean cancer, it could signify various conditions. Don't worry immediately. Other symptoms might occur, such as constant exhaustion, appetite fluctuations, or discomfort. Common reasons include stress, thyroid problems, or diabetes. However, to be certain, seeking professional medical evaluation is essential.
Answered on 23rd July '24
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Today I had done my cbc test and this is my result COMPLETE BLOOD COUNT (CBC) Method :- Photometry , Electrical Impedance & VCS Specimen :- EDTA Whole Blood Method :- Photometry , Electrical Impedance & VCS Specimen :- EDTA Whole Blood Method :- Photometry , Electrical Impedance & VCS Specimen :- EDTA Whole Blood Method :- Photometry , Electrical Impedance & VCS Specimen :- EDTA Whole Blood Test Name (Method , Specimen) Result Units Biological Reference Interval Haemoglobin (Photometric , EDTA) 14.7 g/dL 13 - 17 g/dl PCV (Calculated, EDTA) 43.1 % 42 - 52 % R.B.C Count (Electrical Impedence , EDTA] 4.70 M/cumm 4.50 - 6.50 M/cumm MCV (Derived from RBC, EDTA) 91.8 fL 82 - 98 fL MCH (Calculated, EDTA) 31.3 pg/cell 26 - 34 pg/cell MCHC (Calculated, EDTA) 34.0 g/dL 32 - 36 g/dL RDW (Derived from RBC, EDTA) 13.9 % 11.5 - 14.5 % TLC (Electrical Impedence , EDTA) 3,100 /cumm 4000 - 11000 /cumm Platelet Count (Electrical Impedence , EDTA] 0.97 lakh/cmm 1.40 - 4.00 lakh/cmm Mean Platelet Volume -MPV (Electrical Impedence, EDTA) 16.7 fL 7.4 - 11.4 fL Differential Leucocyte Count - DLC (VCS , EDTA whole blood) Differential Leucocyte Count - DLC (VCS , EDTA wh ole blood) Differential Leucocyte Count - DLC (VCS , EDTA wh ole blood) Differential Leucocyte Count - DLC (VCS , EDTA wh ole blood) Neutrophils 50 % 50 - 62 % Lymphocytes 40 % 25 - 40 % Monocytes 08 % 3 - 7 % Eosinophils 02 % 0 - 3 % Basophils 00 % 0 - 1 % Absolute Leucocytes Count ** Absolute Neutrophils Count . 1,550 /mm3 3000 - 7000 /mm3 Absolute Lymphocyte Count . 1,240 /mm3 1500 - 4000 /mm3 Absolute Monocytes Count 248 /mm3 100 - 500 /mm3 Absolute Eosinophils Count . 62 /mm3 0 - 700 /mm3 Absolute Basophils Count 00 /mm3 15 - 50 /mm3 N-RBC 00 /100Wbc's .. RESULT RECHECKED Kindly correlate with clinical find ings. RESULT RECHECKED Kindly correlate with clinical find ings. RESULT RECHECKED Kindly correlate with clinical find ings. End of Report Plz tell me my my levels high and low in this is this cancer and platelet size also increased
Male | 23
The results of your blood test are nearly within the normal limits. You have a low platelet count, which can be caused by different factors including infections or drugs. Equivalent mean platelet volume does not suggest cancer. It could perhaps be indicative of disorders like platelet destruction. If you do feel difficulties such as abnormal bleeding or bruises, do consult a hematologist.
Answered on 23rd Nov '24
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One person has a cut on his hand . It was bleeding. I ate food from his hand. If that person is hiv positive. Does it transfer to me??
Female | 48
HIV is primarily transferred through some body fluids like blood. If someone with a cut on their hand eats saliva-containing food, the saliva does not carry enough virus to infect you. Being cautious will make sure to see out for symptoms include flu-like illness and talk to your doctor if you are concerned.
Answered on 16th July '24
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