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Yes, fluid exchange may happen even though one uses a condom. In case your worries are regarding it, the most advisable thing to do is to keep an eye on yourself for any symptoms that are not normal for you, such as the ones mentioned as itching, burning, or unusual discharge. One of the advantages of being aware of how your body is functioning is that noticing any changes can help you determine whether it is necessary or not to go for further advice. 

Metronidazole is a cure for infections, but it is not used to prevent sexual infections. Unprotected sex could be avoided by using birth control. Sexually transmitted infections can occur by germs that are transferred during sex without a condom. Proper use of protectors such as condoms and regular medical check-ups should be covered. You can also see a doctor who can give you the right medicine if you think you are infected.