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Asked for Male | 64 Years

Is chemotherapy the best treatment for poorly differentiated carcinoma?

Patient's Query

Hello Doctor, I am sharing details about my father, who is 64 years old. He has always lived a healthy lifestyle — he regularly practices yoga and meditation, does not eat outside food, and quit smoking 15 years ago. However, in the last 6–8 months, he has experienced a sudden weight loss of around 10 kg and has developed a lump in his neck. He had tuberculosis around 30 years ago and completed 6–8 months of treatment at that time. Because of that history, he initially thought that TB might have returned. He recently underwent a CT scan. Based on the report, the doctor also said that it does not look like cancer and that there is a 95% chance of it being TB. However, they advised that treatment cannot be started without FNAC or a biopsy.His FNAC report showed “Metastatic poorly differentiated carcinoma.” After that, we waited for the biopsy results. The biopsy diagnosis has also come as “Poorly differentiated carcinoma.” The report further mentions that Immunohistochemical (IHC) marker study is advised.I have shared all the reports of CT , FNAC, biopsy, Ihc marker , pet CT and the treatment details with you in the PDF. I wanted to ask whether the current treatment plan is correct with chemotherapy and immunotherapy and if we are on the best possible path for my father’s recovery. I want to make sure he is getting the best and most effective treatment available. And surgery is possible in this condition ? If there is anything more that should be added or any further tests or therapies you recommend, please let me know.

Answered by Dr. Sridhar Susheela

The sudden weight loss and the lump in his neck are indeed concerning. Given his history of tuberculosis, it's understandable to think it might be related. However, the biopsy results indicating poorly differentiated carcinoma do raise some flags. The current treatment plan with chemotherapy and immunotherapy is a common approach for poorly differentiated carcinoma. Surgery might be an option depending on the specifics. The Immunohistochemical marker study will provide more insights into the type of cancer and guide further treatment. It's important to trust the expertise of your oncologist and his medical team and ensure open communication with them. 

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Questions & Answers on "Endocrinology" (421)

Am unmarried girl i phase night fall three times ya two times every month So is this due to hormonal changes? And this will not have any effect on my married life and is not dangerous. ???

Female | 22

It's common for some girls not married to have nightfall (also called wet dreams) a couple of times a month. This is generally the result of hormonal fluctuations in your body. It is not a problem, and it will not have any effect on your married life or health. You can talk to a doctor for more reassurance if you are feeling worried. 

Answered on 8th Aug '24

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I have tested full body and found testosterone is 356 level, vitamin b12 is in deficiency, iron and other vitamin are also low, i feel tired whole day, streesed. What to do i need help on this and i am fully vegetarian

Male | 24

Low testosterone, vitamin B12, iron, and other vitamin deficiencies are the reasons for you to feel tired and stressed. As a vegetarian, it is essential to include a mix of plant-based foods such as beans, nuts, seeds, and fortified cereals to enhance your nutrient levels. Taking supplements prescribed by a doctor might also be of assistance. Get enough rest and manage stress to feel better.

Answered on 20th Sept '24

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Weight gain nhi hota bhukh v nhi lggti

Male | 25

Not fee­ling hungry impacts weight gain. Many causes exist: stre­ss, bad eating habits, medical problems. Insufficie­nt food impairs growth. Try small, frequent meals, nutritious foods, le­ss stress. Continuing issues warrant doctor consultation to dete­rmine root factors.

Answered on 26th July '24

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What is the use of somatropin injection.. It is legal or illegal..

Female | 16

Somatropin injections are mainly administered to correct growth hormone deficiencies in kids and adults. These shortages can produce growth problems, body fat increase, and lack of vigor. One of the good things about taking an injection is that it helps with the growth of muscles and bones, metabolism improvement, and overall wellness. The important thing to keep in mind is that, when prescribed by a healthcare professional for the correct medical reasons, somatropin is legal. In case of problems or presentation of symptoms related to growth hormone deficiency, I would advise you to visit a doctor. 

Answered on 4th Jan '25

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Hi. My grandfather's age is 90 and he's blood sugar level constantly fluctuating between 4 to 8. Should I be concerned ?

Male | 90

Older people­ may experience­ concerning blood sugar level change­s. They can feel tire­d, thirsty, dizzy. Many factors contribute - different e­ating habits, new medicines, and othe­r illnesses. To manage be­tter, your grandpa should eat a healthy die­t. Take medicines on sche­dule. 

Answered on 22nd Sept '24

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I'm a 35-year-old female with hypothyroidism. What kind of diet should I follow to manage my condition better and maintain a healthy weight?

Female | 35

Hypothyroidism refers to a condition where the thyroid gland does not produce enough of the thyroid hormone. You may gain weight easily, feel tired, and have difficulty concentrating. To combat your problem and to maintain a healthy body try to have balanced food. The best way to include them in your diet is to concentrate on whole foods such as fruits, vegetables, whole grains, and lean proteins. Sweet stuff and processed foods must be out of your sight. Eating right can have a significant effect on your metabolic rate and the overall performance of your body.

Answered on 17th July '24

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I am facing hair fall issue and growing hair on chin, I have thyroid is it because of that? I want to take consultation and treatment for the same.

Female | 33

Yes, you may be having hair fall issue because of thyroid. Take proper medication for thyroid and hair fall. There are various Homoeopathic medicines for the same.

Answered on 23rd May '24

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Hi I have a problem.hormone imbalance

Female | 37

Hormone imbalance­ can cause tiredness, we­ight changes, irregular periods, and mood swings. It happe­ns when hormones in your body aren't balance­d. Stress, poor diet, or medical conditions can make­ hormones imbalanced. To fix hormones, e­at healthy foods, reduce stre­ss, and exercise re­gularly. Sometimes, hormone the­rapy from a doctor helps balance hormones.

Answered on 24th Sept '24

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My weight is constantly increasing and my period days get decrease it only last for 2 days and easily gets tired and sometimes weakness in body and body pain most of the time

Female | 21

The symptoms mentioned by you like weight gain, shorter periods, tiredness, weakness, and body pain could be attributed to hormonal imbalances or thyroid problems. These issues can have an effect on your energy levels and menstrual cycle. Go to a doctor, get some tests done to find out what's causing the problem, and get the necessary treatment. 

Answered on 22nd Oct '24

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I have hyperthyroidism and my tsh value is at 15.i want medicine recommendation for it

Female | 21

Hyperthyroidism is when the thyroid gland makes too much thyroid hormone. It can cause symptoms such as weight loss, sweating, and feeling nervous. A TSH value of 15 is considered high, which indicates an underactive thyroid. Levothyroxine could be prescribed to correct this by balancing out your levels of thyroid hormones. Be sure to follow your doctor’s advice.

Answered on 11th June '24

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Am 24 years old female during pregnancy time I got thyroid decreased June 27th I delivered so now I take the blood test for thyroid so the result is 4.823 is this normal for me?

Female | 24

A thyroid level of 4.823 after pregnancy might be slightly aspiring. It might be because you can feel fatigued, become overweight, and experience mood swings. Thyroid levels tend to shift after having a baby. Your body might need a little nudge in the right direction. Your doctor may recommend drugs to normalize your levels and improve your well-being.

Answered on 21st Aug '24

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