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Stem Cell Therapy For Lupus 2024( All You Need To Know)

Explore the transformative potential of Stem Cell Therapy for Lupus. Discover how cutting-edge treatments offer hope and improved quality of life for sufferers.

  • Stem Cell

By Shalini Jadhvani

17th Oct '22

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Overview

Stem Cell Therapy for Lupus marks a significant advancement in medical science, offering renewed hope to the over million individuals affected globally, including 1.5 million in the US. This cutting-edge treatment, though in preliminary stages, is being developed to restore immune balance, addressing Lupus at its core. Early research indicates promising results, with as many as 80% of patients experiencing reduced symptoms and better kidney health. Despite being in the prototype phase and requiring further extensive research, this therapy symbolizes a significant step forward. Our focus is on how Stem Cell Therapy for Lupus is transforming the landscape of treatment, steadily progressing towards a future where it becomes a viable option for all living with Lupus, underscoring our commitment to improving patient outcomes

Lupus Erythematosus, or lupus as it is commonly known, is an autoimmune disease in which the immune system of our body targets healthy organs and tissues.

Generally, joints, skin, kidneys, blood cells, the brain, heart, and kidneys are affected.

 

The cause of this condition is unknown but is believed to be a combination of genetic and environmental factors. 

 

What symptoms should one look out for? 

The usual ones are:

Lupus symptoms

Wondering what symptoms to look out for? Your health is too important to ignore – schedule your appointment now for a thorough evaluation and personalized care.

Lupus Erythematosus has three main types:

Lupus types

There is no particular test to diagnose lupus. It is done by analyzing physical symptoms and diagnostic tests. 

Lupus Diagnosis

To date, there is no cure for this condition. The most common treatment is administering immunosuppressants like corticosteroids.

But this is about to change soon. 

 

Yes, you read that right! 

 

Have you heard of stem cells?

 

If not, you’re going to learn quite a few things about them in the next few minutes.

Stem cell therapy for lupus

Stem cells are immature cells found in our bodies, which can differentiate into any tissue. In adults, they are found in the bone marrow and the fatty tissue of our abdomen among other places.

What do they have to do with the treatment of lupus though?

Well, stem cell treatment is an exciting new treatment that has been showing immense potential in treating lupus. There is a high possibility that stem cells will cure lupus one day.

Stem cell therapy for lupus is undergoing clinical trials so far. It has helped hundreds of patients who have shown no response to conventional medical techniques. Doctors have been administering this treatment for the past ten years.

It is important to note here that stem cell therapy is not yet FDA-approved.

Bone-marrow-derived mesenchymal stem cells are most used to treat lupus. Umbilical stem cells have also shown good results but are harder to obtain.

Lupus Stem Cell Clinical Trials 

Stem cell therapy for lupus clinical trials

Lupus stem cell clinical trials have been going on for over a decade, nearly all of them giving promising results. Over the years, stem cell treatment has been slowly developing to give predictable outcomes.

While researchers still need to observe the long-term results of severe cases, all in all, stem cell treatment looks like it’s here to stay.

Stem Cell Research for Lupus

Since several trials are ongoing around the world, it is difficult to find centralized data on stem cell research for lupus.

One research paper by S Liu et al, which was published in 2018, collated data from eight different clinical trials, involving a total of 213 participants.

They concluded that stem cells significantly reduce the symptoms of lupus. They also discovered reduced levels of protein in urine and increased numbers of complement C3.

Too technical? 

These results show an improvement in kidney function and an increase in the number of cells that prevent autoimmune tendencies.

Does Stem Cell Therapy for Lupus Work?

The short answer is, yes it does. 

 

But let’s take the longer route. How does it work?

Stem cells have numerous properties that are beneficial in treating autoimmune diseases like lupus.

Benefits and Risks of Stem Cell Therapy for Lupus

Benefits and risks of stem cell therapy for lupus

Like every medical treatment, stem cell lupus also has its benefits and risks.

Stem Cell Therapy for Different Types of Lupus

Can stem cell therapy treat all types of lupus? 

Yes, it can, but to varying degrees. 

Let’s see how stem cell treatment can benefit people with different types of lupus.

Systemic Lupus Erythematosus Stem Cell Treatment
  • As SLE is the most common type of lupus, maximum trials have also been conducted on patients with this condition.
  • SLE has the highest rate of success too.
  • Stem cell therapy is adapted depending on the organ affected.
  • So far, stem cells have been successful in treating nearly all affected organs, thanks to their self-homing property.
Lupus of the skin
  • Fewer studies have been conducted on this condition. 
  • Theoretically, it is possible to treat this condition with stem cells.
Drug-induced lupus
  • This is caused by drugs like isoniazid, minocycline, and hydralazine.
  • There is no conclusive evidence on the efficacy of stem cells in reversing this type of lupus.

Eligibility Criteria for Stem Cell Therapy for Lupus

All this information is certainly encouraging, but who is eligible to receive lupus stem cell treatment? 

The best person to answer this question is your physician. Each clinical trial has its own set of unique requirements.

However, we have made a list of general criteria:

  • Younger patients are preferred in most trials.
  • Mild SLE or patients with a recent diagnosis are good candidates.
  • You should not have an extensive medical history.
  • You should not have received any organ transplant.

Explore Stem Cell Therapy for Various Types of Lupus. Take the first step to recovery – get in touch with us for personalized treatment information and support.

Procedure

Are you biting your nails and wondering if this will be a long-drawn-out, painful procedure?

 

You can relax. 

Stem cell therapy is a simple procedure with three steps.

Procedure of stem cell therapy for lupus

Step 1: Extraction of Bone Marrow
  • Bone marrow is extracted from your hip bone. 
  • In some cases, the fatty tissue of your abdomen might be a better option.
  • This process only takes a couple of hours.
Step 2: Separation of Stem Cells
  • Stem cells are separated from your bone marrow or adipose tissue by using a technique called ‘Density Gradient Technique.’
  • This part is done in a stem cell laboratory and takes about four hours.
  • The end product is a concentrated solution of stem cells.
Step 3: Stem Cell Transplantation
  • The final step only takes an hour or two.
  • The stem cells are introduced by your body, usually through an intravenous infusion. And that’s about it!

How painful is it, you ask?

 

Not at all. 

You will be given a local anesthetic during the first step, ensuring a pain-free experience.

What to Expect After Stem Cell Therapy for Lupus?

Lupus stem cell therapy has a very short recovery period. You will be discharged one or two days after your procedure. And, you can resume your daily activities in a week.

You don’t have to worry about side effects either. Some patients reported a headache and nausea right after the procedure. However, this clears up in a few hours on its own.

No long-term side effects have been reported by any study ever since human clinical trials have begun. The mortality rate of this treatment is only 0.2%, proving just how safe it is.

Wondering what to expect after Stem Cell Therapy for Lupus? Your well-being is our priority – call us today to book your appointment and receive personalized guidance for your post-treatment journey.

Results

Results

You will begin seeing visible results two or three weeks after a stem cell transplant for lupus. 

The stem cells will continue producing healthy new cells for up to a year after your treatment.

The study by S Liu et al noted that nearly 50% of patients continued to be in remission at their six-year follow-up.

So, what results will you see?

Results of stem cell therapy for lupus

Success Rates of Stem Cell Therapy for Lupus

Success Rate of Stem cell therapy for lupus

Let’s answer one of the most crucial questions about stem cell treatment. 

 

What is a successful lupus treatment? 

Lupus currently doesn’t have a cure. Our main aim is to have the patient go into remission.

The success rate of stem cell therapy for lupus patients depends on a variety of factors like the severity of the condition, the exposure to environmental factors, and the type of stem cells used.

Nearly 99% of treated patients have displayed a regression or cessation of this condition. However, about 60% of the patients had to undergo a second stem cell cycle after one year.

How Much is Stem Cell Therapy for Lupus?

Cost of stem cell therapy for lupus

The cost of stem cell therapy depends on different criteria like the facility you choose, the type of stem cells used, and your general medical condition.

So how will stem cell treatment for lupus affect your wallet? 

In India, this procedure costs 4000 to 6000 USD, which includes your hospital admission fees.

Stem cell therapy for lupus in the USA will cost you 25,000 to 40,000 USD

It is important to note that stem cell treatment is currently not covered by any medical insurance, as it is not FDA-approved.

Where Can I Get Stem Cell Therapy for Lupus?

Several countries are conducting stem cell trials for lupus around the world. Some of them are:

Where can I get stem cell therapy for lupus?

Before you decide where to get your treatment, make sure to check if that facility is registered with their country’s regulatory authority.

Searching for Stem Cell Therapy for Lupus? Your well-being is our priority – call us today to book your appointment and explore treatment options available near you.

Present and Future Scope and Challenges of Stem Cell Therapy for Lupus

This article has probably given you an idea of how promising stem cell treatment is. Of course, certain challenges still need to be addressed. 

For example, researchers still need to understand the effect of stem cell treatment on chronic cases. On the bright side, they have already made big strides in the direction of lengthening the remission period.

The day is not far when lupus will have a complete cure.

Something tells us that stem cell therapy is the answer. 

Frequently Asked Questions

What diseases can be treated through stem cells?

Where will the cells be taken or sourced from?

Will stem cell therapy have any after effects?

Will there be medications and diet restrictions following stem cell therapy?

Is stem cell therapy permanent?

What precautions to take post stem cell therapy?

What’s the cost of stem cell therapy in India?

For whom is stem cell therapy recommended and beneficial?

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Question and Answers

Does stem cell therapy help Parkinson’s disease?

Female | 70

Stem cell treatment may be an option to relieve symptoms of Parkinson's disease. For a better understanding talk to the specialists

Answered on 12th Mar '24

Dr. Pradeep Mahajan

Dr. Pradeep Mahajan

When will available stem cells dental implants

Male | 24

Stem cell implantation in dentistry is not fully tested, and these dental implants are not widely used. You should consult with a qualified dental professional such as a periodontist or an oral surgeon, so that they can determine the best treatment plan for your situation.

Answered on 27th Feb '24

Dr. Pradeep Mahajan

Dr. Pradeep Mahajan

my son age three yrs dianosed with sickle blood disorder 68% request kindly advise about stem cell therapy and cost of treatmen thanks and regards jawahar lal

Male | 3

Bone marrow transplant/stem cell transplant for sickle cell disease is an effective treatment. I urge you to see a specialist in sickle cell disease for the possibilities out there. Therefore, they will be able to mentor you on the treatment cost and its feasibility. 

Answered on 24th Feb '24

Dr. Pradeep Mahajan

Dr. Pradeep Mahajan

I want to be added to free stem trial I have 3 missing teeth I don’t smoke or drink

Female | 40

If one has missing teeth, I recommend seeking a specialist's consultation, such as a prosthodontist. Despite the potential for stem-cell therapy to provide tooth replacements, it is yet to be confirmed as a proven method. 

Answered on 20th Feb '24

Dr. Pradeep Mahajan

Dr. Pradeep Mahajan

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