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Male | 27

Why is my Vyvanse not working after taking Omeprazole for GERD?

Hi so I took omeprazole for 1 month because of GERD, now I’m off it and back on Vyvanse but my vyvanse doesn’t work at all after the omeprazole, it doesn’t activate, how come?

Dr. Samrat Jankar

Surgical Gastroenterologist

Answered on 3rd Feb '24

Omeprazole decreases the bioavailability of Vyvanse by blocking its uptake.
For the GERD, it is recommended to see a gastroenterologist for its management and psychiatrist in case of prescribing Vyvanse.
 

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