Some people have a congenital anomaly characterized by the lack of an LSVC. It is usually not considered as alarming in itself and may have no serious clinical implications. Tthe person should talk about this finding with their healthcare provider – preferably a cardiologist ― so that it will be properly recorded in his or her medical history and to exclude any related anomalies or implications pertaining specifically for him or her.

The absence of a left superior vena cava is a rare anatomical variation where the vein is not located in its usual position. It is generally considered a normal variant and not inherently good or bad. While it usually doesn't cause health issues, it can bring challenges during certain medical procedures.