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Stem Cell Treatment for TBI

Understand how stem cell therapies can offer a new horizon for treating traumatic brain injuries (TBI). Learn about the processes, types, benefits, and risks.

  • Stem Cell
By Sakshi More 9th Apr '24 21st Apr '24
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Traumatic brain injury (TBI) occurs when a sudden trauma damages the brain, commonly due to accidents, falls, or sports impacts. TBIs range from mild concussions with brief brain dysfunction to severe cases causing prolonged unconsciousness or lasting brain damage. Symptoms vary and can include headaches, confusion, and vision problems. 

Did you know?

Traumatic brain injury (TBI) is a significant cause of mortality and disability worldwide. 

  • TBIs cause approximately 30% of all injury deaths in the U.S.
  • Each year, there are about 2.8 million TBI-related emergency department visits, hospitalizations, and deaths in the U.S.
  • Globally, nearly 69 million individuals sustain a TBI annually.
  • India has the highest rate of head injury in the world. More than 100,000 lives are lost every year due to head injuries, with over 1 million people suffering from severe head injuries.
  • One person dies in India every 6 to 10 minutes due to TBI.

Have you also faced the same problem?

Stem cell treatment for TBI holds significant promise, but it is not yet considered a cure for traumatic brain injury. Current research focuses on its potential to improve symptoms and quality of life by repairing damaged tissues and reducing inflammation in the brain. The ultimate goal is to restore some degree of normalcy in brain function, but complete cures are still a subject of ongoing research. Many stem cell institutes and healthcare experts worldwide recommend this approach. Despite ongoing research, this method has benefited numerous patients and shown safety and effectiveness in various studies for different conditions.

Traumatic Brain Injury Types and How Stem Cells Can Help

1. Concussion: A mild brain injury with symptoms like headaches and confusion.


How stem cells can help: Stem cells could help heal the brain faster and reduce symptoms.

2. Contusion: A bruise on the brain caused by a hit to the head, can be serious.

How stem cells can help: Stem cells might repair damaged brain cells and blood vessels.

3. Diffuse Axonal Injury: Severe injury from shaking or rotation can cause coma.

Diffuse Axonal Injury
How stem cells can help: Stem cells could fix nerve cells and improve brain connections.

4. Penetrating Injury: An object goes through the skull and brain very severely.

Penetrating Injury

How stem cells can help: Stem cells might rebuild brain tissue and lessen other damage.

Wondering how and when to consider Stem Cell Therapy? Don't worry we have got you!

Eligibility Criteria for Stem Cell Treatment for TBI

Eligibility criteria for stem cell treatment for traumatic brain injury (TBI) typically include the following points:

  • Severity of Injury: If you have moderate to severe TBI, where traditional treatments have limited effectiveness.
  • Stable Condition: You must be medically stable enough to undergo the treatment without severe risks.
  • Time since Injury: Treatment is usually more effective if started some months after the injury to allow initial natural healing.
  • Age and Overall Health: Younger patients and those in good health, without chronic diseases like diabetes or heart disease, may respond better.
  • Absence of Active Infections: Patients must be free of active infections to minimize the risks associated with stem cell transplantation.
  • No History of Cancer: Individuals with a history of cancer may not be eligible due to potential risks of cell proliferation.

Curious about the treatment options from stem cells for tbi treatment? Read further to understand more about it.

Types of stem cell used for TBI treatment

For treating traumatic brain injury (TBI), several types of stem cells are commonly used:

  • Neural Stem Cells (NSCs): These cells specialize in becoming brain cells and helping repair brain tissue.
  • Mesenchymal Stem Cells (MSCs): Found in bone marrow and other tissues, these cells reduce inflammation and aid in healing.
  • Induced Pluripotent Stem Cells (iPSCs): Adult cells reprogrammed to develop into any type of cell, including brain cells.

Each type plays a role in supporting recovery and repairing damage in TBI treatments.

Want to know which type you can consider for your therapy? Book an Appointment now and talk to our experts!

Procedure of Stem Cell Treatment for TBI

  1. Evaluation: Medical assessment to determine treatment suitability.
  2. Stem Cell Sourcing: Select and prepare the appropriate stem cells.
  3. Cultivation: Cultivate stem cells to required quantities.
  4. Administration: Inject stem cells either directly into the brain or intravenously.
  5. Monitoring: Use imaging and follow-ups to track treatment effectiveness.
  6. Rehabilitation: Continue with rehabilitation therapies to support recovery.

What to Expect After Stem Cell Treatment for TBI

  • Initial Recovery: Short-term recovery may include immediate post-procedure symptoms such as mild discomfort or swelling at injection sites.
  • Monitoring: Specialists like neurosurgeons may also Regular medical evaluations to monitor the integration of stem cells and assess any changes in neurological function.
  • Gradual Improvement: Potential gradual improvements in cognitive, motor, and sensory functions over weeks to months.
  • Rehabilitation: Ongoing rehabilitation therapies to maximize recovery of skills and adaptation to any changes.
  • Side Effects: Observation for any adverse effects, including immune reactions or inflammation.
  • Long-Term Follow-up: Long-term follow-up appointments to evaluate the lasting impacts of the treatment and adjust care plans as needed.

Benefits and Risks of Stem Cell Treatment for TBI



Potential restoration of cognitive and physical functionsUnpredictable side effects, including immune reactions
Reduction in inflammation and protection from further damagePossibility of cells proliferating abnormally
Potential to improve quality of life significantlyHigh costs and lack of insurance coverage in many cases

Do you want to seek long-lasting relief from traumatic brain injury pain? Contact us now! and learn more about stem cell therapy. 

Cost of stem cell treatment for traumatic brain injury

In India, stem cell treatment for TBI costs between 8,000 and 12,000 USD. Compared to this, in the United States, the costs can range from $15,000 to $50,000 per treatment session.

Based on the types of treatments, here is the approximate cost of Stem Cells for tbi in India:

Type of Stem Cell Treatment

Approximate Cost (USD)

Neural Stem Cells (NSCs)$10,000 to $15,000
Mesenchymal Stem Cells (MSCs)$8,000 to $12,000
Induced Pluripotent Stem Cells (iPSCs)$12,000 to $20,000

Note: These costs are dynamic. Depending on the provider's expertise, location, insurance, and treatment protocols, they may vary.

Let us read together and understand more about these factors below!

Factors affecting the cost of stem cells for TBI 

The cost of stem cell treatment for traumatic brain injury (TBI) can be influenced by several key factors:

  • Type of Stem Cells: Different stem cells have varying extraction and preparation costs.
  • Treatment Protocol: More complex or extensive treatments generally cost more.
  • Location: Costs vary by country and healthcare facility, with specialized centers often charging more.
  • Additional Procedures: Costs can increase with necessary diagnostic tests and follow-up care.
  • Insurance Coverage: The extent of insurance coverage can significantly affect out-of-pocket expenses, as many insurers do not cover experimental treatments.
  • R&D Costs: Newly developed treatments may be more expensive due to research and development costs.

To Know more in-depth about expenses, Schedule a Consultation with the experts today!

Success Rates of Stem Cells for tbi

  • In India, clinical studies indicate that  MSC transplantation holds potential as an effective treatment for TBI patients.
  • Additionally, umbilical cord mesenchymal stem cell transplantation has safely and effectively improved neurological outcomes in TBI cases.
  • While exact success rates can vary, stem cell therapies have shown promise in mitigating brain injury pathology in adult and pediatric TBI models.


Stem cell treatment for TBI is an exciting frontier in medical science with the potential to alter the treatment landscape for traumatic brain injuries significantly. Although it is not a guaranteed cure, its ability to regenerate damaged brain tissue offers hope where traditional treatments have been limited. Ongoing research and clinical trials continue to shed light on its efficacy and refine its application, making it a promising option for many TBI patients.


  1. How safe is stem cell treatment for TBI?

Stem cell treatments are generally considered safe but carry risks like any medical procedure, including potential immune reactions and the growth of unwanted cells.

  1. How long does it take to see results from stem cell therapy for TBI?

Results can vary widely; some patients may see improvements within months, while others may take longer based on the severity of the injury and the type of stem cells used.

  1. Is stem cell therapy for TBI covered by insurance?

Coverage varies by insurance provider and policy. Currently, many insurers consider stem cell therapy for TBI experimental and may not cover the costs.

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Question and Answers

Does stem cell therapy help Parkinson’s disease?

Female | 70

Stem cell treatment may be an option to relieve symptoms of Parkinson's disease. For a better understanding talk to the specialists

Answered on 23rd May '24

Dr. Pradeep Mahajan

Dr. Pradeep Mahajan

When will available stem cells dental implants

Male | 24

Stem cell implantation in dentistry is not fully tested, and these dental implants are not widely used. You should consult with a qualified dental professional such as a periodontist or an oral surgeon, so that they can determine the best treatment plan for your situation.

Answered on 23rd May '24

Dr. Pradeep Mahajan

Dr. Pradeep Mahajan

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