This may happen due to many reasons, such as dry skin, eczema or allergies and contact dermatitis. Itch sensations may also be heightened at night due to the natural circadian rhythm of the body. It is advised to apply a hypoallergenic moisturizer before going to bed, which can mitigate symptoms of dry skin. It is possible to manage allergic reactions by identifying potential triggers such as certain soaps or fabrics and avoiding them. If chronic or aggravating, it is so recommended to consult a dermatologist for an in-depth evaluation and tailored treatment options targeting the true cause of nighttime scratch.

It could be for any of the following reasons:

• Hand eczema: Caused by exposure to harmful chemicals and moisture, here you may see cracks, redness, dryness and sometimes blistering too.
• Contact dermatitis: If your itchiness is caused as a result of allergic reactions, it should resolve within in 48-96 hours. But then you would have to identify irritants in order to avoid them.
• Diabetes indication: like if it damages your nerves, or liver and kidney, or if you develop an allergic reaction to medicines.
• Cirrhosis: This condition primarily affects bile, and as a symptom of it you can experience itching, but then you will also experience following symptoms: bone pain, nausea, diarrhea, dark urine and jaundice.
• Nerve disorder: here you have itchy palms at night mostly in the initial days.

You can refer our pages to visit these doctors and get yourself examined:
Dermatologists in India, Neurologist in India, Endocrinologists in India.