Considering that you’ve already undergone creams and syrups without any use, it’s necessary to take into account other alternatives. This white spot can be due to several causes such as a non-dangerous cyst, a fungal infection, or a condition named leukoplakia. Although it is not itching and painless, we would still recommend you to visit a healthcare provider for a correct diagnosis. They may propose a biopsy for the identification of the cause and the best treatment plans for you. Don't forget that a stitch in time saves nine!

Itching on your shoulder and back for so many years, and it's gotten darker recently. Itching can have various causes, like dry skin, allergies, or even a skin condition called eczema. The recent change in color could be due to increased scratching or inflammation. It's essential to have it checked by a dermatologist to rule out any serious concerns. In the meantime, try using a gentle moisturizer and avoid scratching to prevent further darkening. 

Your partner may have diabe­tic foot problems. High sugar levels ove­r time can cause this condition. Some notice­able signs are swelling and dark skin color on the­ foot. You shouldn't ignore it, or it could get very se­rious. To manage this properly, she ne­eds to keep he­r sugar levels under control. Fastidiously cle­aning her feet and we­aring appropriate footwear are also crucial ste­ps.