Stem Cell Dental Implants 2022, Is It The Future of Dentistry?

A smile can light up the darkest of rooms. Every day people lose their teeth for several reasons, be it an injury or negligence. For several centuries, people endured living with less or no teeth. Sure, we now have a few alternatives to replace missing teeth, but they are not always comfortable. They hinder our eating habits and speech. Researchers have been working for decades to overcome this problem. And now, they finally might have an answer. If you want to know how to get back your missing tooth, and yes, your missing smile and confidence also, continue scrolling!

By Shalini Jadhvani

Updated on 23rd, Nov'22

2620 views
Blog Banner Image

Overview

If someone asked you what problem missing teeth cause, you would say an inability to chew, right? 

 

But did you know that missing teeth can also bring a host of other issues with them?

Problems Caused By Missing Teeth

  • Sagging cheeks and aged appearance
  • Speech issues
  • Bone loss of the jaws
  • Gum disease in the remaining teeth
  • Shifting and mobility of remaining teeth
  • Lowered self-esteem

Of course, dentistry has come up with solutions for missing teeth, including:

 

Solutions For Missing Teeth

However, all these solutions could soon be a thing of the past. Researchers have now come up with a brand-new treatment to replace missing teeth—Stem Cell Dental Implants!

 

What Are Stem Cell Dental Implants?

Intrigued? 

 

Let us first understand what a stem cell is. 

Stem Cell Dental Implants

Stem cells are immature cells found in our bodies, that can differentiate into any tissue. They are found in several parts of our bodies, even as adults.

 

The aim of a stem cell dental implant is to regrow missing teeth in the mouth. The most used dental stem cells are obtained from exfoliated baby teeth and wisdom teeth. 

 

Some studies have also been conducted with bone marrow-derived stem cells, as they can differentiate into nearly any tissue of the body.

 

It is important to note here that stem cell dental implants is still an experimental procedure. 

 

It is in the very initial stages of clinical trials and has not received FDA approval yet.

 

Do They Work?

Isn’t this the most crucial question right now? 

 

It’s also a difficult one to answer at present. 

 

Dental stem cell implants have seen great success in animal trials.

 

However, since the clinical trials are very recent, more data is required to reach a conclusive result.

 

But are they a tooth replacement? 

 

Yes, that is the end goal of this treatment. Humans only get two sets of teeth during their lifetime. The first set, or baby teeth, fall out by the age of twelve or thirteen years. 

 

If any teeth from the second set are lost, the affected person will never have a natural tooth in that position again. 

 

This brings us to the next question. 

 

Can teeth grow back after stem cell tooth implants? 

 

Yes, as evidenced in several studies. Doctors have already achieved this feat in animal models and clinical studies. It’s only a matter of time before we see this as a regular dental treatment.

 

How do they work? 

 

Stem cells have a unique ability to repair, restore, and regenerate teeth. A tooth itself is made of three different layers, each of which is created by a different cell. In normal cases, these cells are only found in the embryonic stage.

 

But thanks to recent advances, scientists have figured out a way to induce stem cells to form these cells, resulting in the regeneration of new teeth. 

 

Not just this, stem cells can also induce the formation of blood vessels. By restoring the blood supply to the tooth, it will become fully functional.

 

Can teeth regrow naturally? 

 

The human body is not equipped with the ability to regrow teeth. While artificial replacements are available, with stem cell treatment, researchers finally have hope that a natural replacement will be available in the future.

 

Types of Stem Cells Used in Dental Implants

There are several types of stem cells like embryonic stem cells, bone marrow-derived mesenchymal stem cells, and dental stem cells.

 

Embryonic stem cells are exceptionally effective in treating a variety of conditions including missing teeth. However, the use of embryonic stem cells involves major ethical concerns.

 

Dental stem cells are found in the pulp of both baby teeth and adult teeth. For decades, these teeth were simply discarded after extraction or exfoliation. With this new information, many patients have the option of preserving these teeth for future treatments.

 

At present, baby teeth and wisdom teeth are considered to be the best sources of dental stem cells.

 

Are Stem Cell Dental Implants Available?

Stem cell tooth regeneration is not a mainstream dental treatment at present. Clinical trials for this treatment are expected to start in one or two years.

 

While there is no established timeframe for the availability of stem cell treatment, there is hope that it will be commercially available in the next five years.

 

Stem Cell Dental Implants Clinical Trials

Stem Cell Dental Implants Clinical Trials

Several clinical trials for dental implants are ongoing around the world. One research paper by Christian Morsczeck and Torsten E. Reichert studied the data of several clinical trials. 

 

They noted that dental stem cells obtained from deciduous exfoliated teeth and wisdom teeth have a lot of potential in not just the regeneration of teeth but also the repair of decayed teeth.

 

They also concluded that over the next several years, it will be possible to tailor stem cell dental treatment for each patient according to their needs.

 

 

Present, Future Scope, and Challenges of Stem Cell Dental Implants

While the results of clinical trials have been promising so far, there are certain challenges that need to be addressed before stem cell dental implants become a conventional dental treatment.

 

The most important one is identifying the correct stem cell for the regeneration of teeth. Since the tooth is made up of multiple layers, it is necessary to find a stem cell that can create all three layers, and is available post-natal.

 

The time frame also varies with each study. However, there is a light at the end of this tunnel. Dr. Jeremy Mao, a professor of Dental Medicine at Columbia University Medical Center, published a paper in the Journal of Dental Research, where he described how he had successfully managed to grow a tooth in nine weeks.

 

In the meanwhile, stem cells have also found a use in naturally treating decayed teeth by repairing the dentin layer of the tooth.

 

Eligibility

Unlike most other stem cell clinical trials, the eligibility for stem cell dental implant trials is more relaxed. Of course, each trial will have its own set of requirements. 

 

But some of the general ones are:

 

Eligibility

  • The patient should have a missing tooth
  • The patient should not have an extensive medical history
  • The patient should not have any immunodeficiency or an auto-immune disease
  • The patient should not have extensive gum or bone diseases

 

Benefits and Risks of Stem Cell Dental Implants

Benefits & Risks

Nothing is completely black or white! 

 

The same goes for stem cell dental implants. 

 

Stem cell dental implants have their own set of benefits and risks. 

 

Let’s have a look at them! 

 

BenefitsRisks
  • Relatively non-invasive procedure

 

  • Possibility of infection at the site of injection

 

  • Completely safe procedure

 

  • There is a chance the treatment might not work

 

  • Possibility of regaining a natural tooth

 

  • There is a possibility of rejection if donor cells are used

 

 

Procedure

Now that you’ve got a basic understanding of stem cells, we are sure you’re wondering just what the procedure entails.

Procedure of Stem Cell Dental Implants

 

So far, this procedure has not been conducted on humans, but is expected to start soon. 

 

The proposed procedure will be as follows:

 

ProcedureDetails

Step 1

Extraction of stem cells

  • This will either be done from wisdom teeth (if the patient has lost their deciduous teeth), or from baby teeth.
  • There is also the option of using bone marrow-derived stem cells in some cases.

 

Step 2

Isolation of the stem cells from the remaining pulp tissue.

  • This will be done in a stem cell laboratory.

 

Step 3

Implantation of stem cells

  • This will be done by injecting them into the region of the missing tooth. 
  • A small scaffolding-like structure might be inserted to guide the growth of the tooth.

 

 

Are you worried about the pain? 

 

Don’t worry!

 

All these steps will be done after giving you local anesthesia to ensure that they are pain-free. 

 

What to Expect After the Procedure?

This procedure is very straightforward. You might experience some soreness at the site of the implant once the anesthesia wears off. However, this will only last for a couple of days.

 

You will be allowed to resume your daily activities a couple of hours after the procedure. 

 

You might just be advised to follow a soft diet for two to three days after the procedure.

 

Apart from these precautions, you can expect no other side effects. Stem cell treatment for teeth is completely safe and convenient.

 

Results

Stem Cell Dental Implants Results

When will the tooth be completely formed, you ask? 

 

Based on the current projections, you will see your brand-new tooth completely formed in your mouth within nine weeks!

 

This tooth is expected to be functional, so you can also start chewing with that tooth after nine weeks.

 

Success Rates of Stem Cell Dental Implants

Success Rates of Stem Cell Dental Implants

While stem cells have not yet been used to grow a human tooth in the mouth, they have been used to grow the jawbone successfully. The success rate for this procedure is 91-95%.

 

Dental implants are expected to have similar success in human clinical trials, which will begin in the next couple of years.

 

Additionally, the repair of teeth with stem cells is also expected to have a success rate of over 90%.

 

Yes, you read that right!

Stem Cell Dental Implants Cost

Cost

Stem cell dental implants price is expected to be 300 to 700 USD in India. This cost will include stem cell banking expenses for a short period of time. 

 

However, we will only know the actual prices once human trials begin.

 

Where Can I Get Stem Cell Dental Implants?

Where can I get Stem Cell Dental Implants?

Several countries like India, the USA, the UK, and China are expected to start human trials for this treatment soon. We would like to add a word of caution here. 

 

Before joining any trial, you should thoroughly check the credentials of the facility involved. 

 

You should also ensure that the trial is registered with the country’s regulatory authority.

 

Stem Cell Dental Implants vs Dental Implants

Dental Implant v/s stem cell dental implants

How are stem cell dental implants different from conventional dental implants, you must be wondering, right? 

 

Let’s find out.

Stem Cell Dental ImplantsDental Implants
Made of our body tissuesMade of metal
Less invasive and convenientMore invasive and troublesome
Nine weeks are required for the formation of a complete toothGenerally, three to six months are required for the implant to become functional
Expected to be more cost-effectiveExpensive
Completely safe to surrounding tissuesSometimes, implants cause damage to the surrounding nerves and tissues

 

Will Stem Cells Replace Dental Implants?

Stem cell dental implants present an excellent solution to replacing missing teeth. By regenerating a natural tooth, dentists will not only be able to fill the empty area but also be able to return the function of your tooth. 

 

Although this might still take a few years to accomplish, once it’s done, conventional dental implants will be rendered redundant. Stem cell dental implants are expected to be superior to conventional dental implants while being cost-effective.

 

Are you excited about the future of dentistry?

 

Very soon, avoiding smiling because of embarrassment caused by a missing tooth would be a thing of the past! 

 

And smiling with confidence would become a thing of the present, all thanks to the wonderful innovation called “ Stem Cell Dental Implants!” 

 

 

 

References:

 

https://www.tandfonline.com/doi/abs/10.1080/14712598.2018.1402004

 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000521/

Frequently Asked Questions
Question and Answers (264)

Can tooth decay be reversed?

Asked anonymously on 4th September, 2022 at 6:40 pm

The short answer is “no” but the long answer is “sort of.”  Here’s why:


The earliest stage of tooth decay or a cavity is demineralized enamel. The outer layer of enamel becomes weak and soft, due to acids and plaque biofilm coming into contact with it on an extended basis.

Fortunately, demineralized enamel can — to an extent — be remineralized before a physical cavity (hole) ruptures through the surface.


What are some ways to help this happen?

  • Improved hygiene and plaque removal on an everyday basis
  • Protective dental sealants over deep grooves and fissures, which are someof the most cavity-prone surfaces
  • Drinking fluoridated tap water throughout the day
  • Supplementation with a prescription strength fluoride or mouthrinse, providedby your dentist
  • Use of everyday oral hygiene products that contain fluoride
  • Eating more fresh fruits and vegetables, sharp cheddar cheese, and fewerprocessed carbohydrates
  • Eliminating acidic beverages and those that contain natural or artificial-sweeteners

The types of cells that make up your teeth do not re-grow or repair themselves after the tooth is fully developed.

Once a tooth has a physical cavity (opening or hole) inside of it, there is no feasible way to help the enamel grow back on your own. Instead, the cavity will gradually worsen, due to the bacterial infection inside of the tooth structure.


Ideally, you would want to treat the cavity as soon as it’s diagnosed and while it’s as small as possible. When you do, your dentist can place a minimally invasive filling and preserve as much healthy tooth structure as possible.

But untreated cavities will expand to the point that they require larger fillings. Or worse, they will reach into the nerve chamber and create an abscess. What could have initially been treated with a modest restoration now becomes a situation requiring a root canal and a crown

Dr. Kopal   Vij's profile picture
Dr. Kopal Vij

How long does a root canal last without a crown?

Asked anonymously on 5th August, 2022 at 4:59 pm
a root canal done tooth is brittle and can break easily when hard food is chewed .

so root canal will last as long as it doesnot break with pressure of hard food 

by capping the tooth it will not break inspite of having hard food ( depends on quality of cap) 

for more information contact Burute Dental , Pune
Dr. Mrunal Burute's profile picture
Dr. Mrunal Burute

What to eat with a toothache?

Asked anonymously on 5th August, 2022 at 4:54 pm
try warm and soft food 
eg- khichadi , dal rice etc 

advice to get treated from dentist soon


for more information contact Burute Dental , Pune
Dr. Mrunal Burute's profile picture
Dr. Mrunal Burute

How often should you get dental xrays?

Asked anonymously on 5th August, 2022 at 4:44 pm
only if you want to know the periapical pathology or the spread of cavities.
the exposure of dental x-ray is very minimal so no cause of worry
Dr. Parth Shah's profile picture
Dr. Parth Shah

Why do i need dental x ray?

Asked anonymously on 5th August, 2022 at 4:37 pm
to know the extent & spread of the carious portion within the tooth & the spread in the bone as well 
Dr. Parth Shah's profile picture
Dr. Parth Shah

View more questions on similar topics :

Dental Treatement
Stem Cell
Dr. Darshini Mehta's profile picture

Medically reviewed by Dr. Darshini Mehta - BDS

Relevant