Company logo
Get Listed

Get answers for your health queries from top Doctors for FREE!

100% Privacy Protection

100% Privacy Protection

We maintain your privacy and data confidentiality.

Verified Doctors

Verified Doctors

All Doctors go through a stringent verification process.

Quick Response

Quick Response

All Doctors go through a stringent verification process.

Reduce Clinic Visits

Reduce Clinic Visits

Save your time and money from the hassle of visits.

  1. Home /
  2. Blogs /
  3. Pancreas Transplant for Type 1 Diabetes: Treatment Overview

Pancreas Transplant for Type 1 Diabetes: Treatment Overview

Transforming lives: Pancreas transplant for Type 1 diabetes. Explore breakthroughs, benefits, and life-changing journeys toward freedom from insulin dependence. Learn more.

  • Gastroenterologyy
  • Transplant Surgeryy
By Shweta Kulshreshtha 16th Sept '23 27th Mar '24
Blog Banner Image

Diabetes is a worldwide pandemic and ranks as the seventh leading cause of death in the world. As per the WHO, approximately 1.5 million lives annually are affected by this. It currently affects 537 million people, about 10.5% of the world’s population. It is expected to affect 550 million people by the end of 2030. 

Type 1 diabetes accounts for about 5-10% of diabetics worldwide, with about 15 to 20 new cases per 100,000 developing annually. It often develops in childhood or adolescence and is prevalent in about 1 in 500 children and adolescents.

Studies show that in 2021, there were an estimated 8.4 million patients suffering from Type 1 diabetes. 

Type 1 diabetes is a chronic autoimmune condition wherein the immune system mistakenly attacks and destroys the insulin-producing cells of the pancreas. Due to this, your body is unable to produce insulin. So, these patients have to rely on insulin injections or pumps to manage their blood sugar levels, as their bodies cannot naturally produce insulin. 

Purpose of Pancreas transplant for type 1 diabetes?

Vector vector isolated illustration of pancreas, duodenum and gallbladder anatomy. human digestive system

Pancreas transplant for Type 1 Diabetes is a remarkable treatment technique. It is a surgical procedure where a healthy pancreas is transplanted from a donor into a recipient with a malfunctioning or absent pancreas. It is typically performed in individuals with severe Type 1 diabetes or other conditions that have led to complete pancreatic failure.

The objective? 

To get that insulin production back on track and potentially eliminate the need 

for insulin injections.

Your health is too important to ignore – schedule your appointment now.

Pancreas Transplant vs. Other Type 1 Diabetes Treatments?

Free vector medical blood glucose measurement

A pancreas replacement for diabetes differs from other treatments. Because it replaces a non-functioning pancreas with a healthy pancreas as compared to insulin treatment.  Although it offers a cure for insulin dependence, it requires lifelong immune suppression and carries some amount of surgical risk. 

Sounds encouraging and wants to know if you qualify for it or not? Read further if you are eligible for a pancreas transplant for type 1 diabetes.

Eligible criteria for a pancreas transplant to treat type 1 diabetes

Free photo close-up doctor completing covid medical form

You are eligible for a pancreas transplant with type 1 diabetes if:

  • You have poorly controlled Type 1 diabetes
  • Are in good overall health
  • You have no contraindications.                                                                                          

Your doctor will consider your overall health, age, and other medical conditions before giving the green light for a pancreas transplant.

Procedures involved in a pancreas transplant for type 1 diabetes

Vector nutrition expert flat illustration of dietitian

The procedure involves the following steps:

  • Surgical removal of your diseased pancreas.
  • Transplanting a healthy pancreas from a deceased donor
  • Connect the donor pancreas to blood vessels and the digestive tract
  • You will be administered immunosuppressive medications to prevent rejection.
  • You will be monitored for complications. 
  • Your medications will be changed if required.

Potential risks and benefits of pancreas transplant for type 1 diabetes

Potential Risks

Potential Benefits

Surgical complicationsless insulin (or none at all)
InfectionImproved blood sugar control achieved
BleedingPotential cure of diabetes
Rejection of the transplanted organEnhanced quality of life
Lifelong immunosuppressive drugsReduction in diabetes-related complications
Shortage of organ donorsImproved overall health

How successful are pancreas transplants in achieving insulin independence for type 1 diabetes patients?

Free vector red arrow going up with bar chart

Insulin independence can be achieved by pancreas transplant for type 1 diabetes patients. It is a viable option for patients showing severe complications of diabetes. The success rate depends on the following factors:

  • Type of transplant
  • Your age
  • Your overall health
  • Quality of donor organ received

Quick glance at different types of pancreas transplants along with their success rates:

ProcedureDescriptionSuccess rate 
Whole pancreas transplantMost common type involves transplanting the entire pancreas from a deceased donor.Insulin independence is achieved at about 50% at 5 years.
Simultaneous pancreas and kidney transplant It involves transplanting both the pancreas and a kidney from a deceased donorInsulin independence is achieved at about 70% in 5 years
Pancreas after kidney transplantIt involves transplanting the pancreas after the patient has already received a kidney transplantInsulin independence is achieved at about 40% in 5 years

Please remember this is a major surgery, with an associated risk of organ rejection. But if you are suffering from severe complications of diabetes, then a pancreas transplant might just be the right solution for you. Talk to your surgeon at a best hospital first for your personalized treatment.

Take charge of your health and your life. Contact us today!

What are the primary complications that can arise after a pancreas transplant for type 1 diabetes?

Vector doctor endocrinologist with patient record syringe vector illustration diabetes medication insulin t...

The primary complications that can arise after pancreas transplantation are:

  • Graft rejection: This is your body's natural response to a new organ. It can occur at any time after the transplant. But commonly it occurs within the first few months. Although the rejection can be treated with medicines, it can also lead to the loss of the graft.
  • Pancreatitis: This is inflammation of the pancreas. Pancreatitis can be caused by rejection, infection, and medication. It is a serious complication, but it is usually treatable.
  • Infection: The risk of infection is especially high after a pancreas transplant. The pancreas is a very vascular organ and it is easily contaminated with bacteria. Serious infections can lead to the loss of the graft.
  • Bleeding:  Major bleeding could be a serious complication.
  • Thrombosis:  It is most common in the vessels that supply the pancreas. It can lead to the loss of the graft.
  • Other complications: 
    • Hypoglycemia (low blood sugar)
    • Hyperglycemia (high blood sugar)
    • Kidney problems
    • Liver problems
    • Heart problems
    • Infections of the urinary tract, lungs, or skin

You can reduce your risk of complications by taking good care of the transplanted organ. This involves taking the prescribed medications, following the doctor's instructions, and avoiding activities that could put the graft at risk.

It is important to talk to your doctor about the benefits and risks, which will help you to make an informed decision.

Recovery process and timeline following a pancreas transplant for type 1 diabetes

Free vector people in hospital isometric design concept with family members visiting sick relative flat vector illustration

Stage of Recovery Timeline Description
Immediate Post-Op1-2 weeksIntensive monitoring in the ICU, focusing on surgical recovery and ensuring graft function.
Hospital Stay2-4 weeksTransfer to a regular room, ongoing monitoring for graft health, and initiation of immunosuppressive drugs.
Treatment with immunosuppressive drugsOngoingDischarge from the hospital, continuing medication regimen, and close outpatient monitoring.
Recovery at home6-12 weeksGradual return to work, exercise, and daily routines with frequent follow-ups with the transplant team.
Resuming Normal Activities3-6 monthsLifelong monitoring for graft function, checking for potential complications, and adjusting immunosuppressants as needed.
Long-Term Follow-UpOngoingVigilance for infection, graft rejection, diabetes-related complications, and side effects of immunosuppressants.

Your well-being is our priority - call us to book your appointment today

Lifestyle changes required for undergoing a pancreas transplant for type 1 diabetes

Free vector healthy lifestyle habits cartoon composition with nonsmoking woman practice stress relieving yoga 8h sleep diet

Some common lifestyle changes you need to make:

  • Taking lifelong immunosuppressant medications: They prevent your body from rejecting the transplanted pancreas.
  • Regular follow-up care: See your transplant doctor regularly for checkups and blood tests.
  • Diet changes: This is required since your body may be more sensitive to changes in blood sugar levels. 
  • Exercising regularly: It will help to control blood sugar levels and improve your overall health.
  • Stress management: This is important as stress can affect blood sugar levels. You could try relaxation techniques, like yoga or meditation.

Please note: All of these you should follow only as per your doctor's advice.

How has medical technology boosted the success of pancreas transplants for type 1 diabetes?

Free vector flat people asking questions illustration

Some of the latest advancements include:

Precision Matching: Enhanced techniques for donor-recipient compatibility selection which reduces the risk of rejection.

Minimally Invasive Surgery: Less invasive surgical procedures result in shorter recovery times and reduced complications.

Immunosuppressive Drugs: More targeted and effective immunosuppressive medications, which minimize the risk of graft rejection.

Organ Preservation: Improved organ preservation methods, extending the viability of the donor pancreas.

Monitoring Tools: Advanced monitoring tools and biomarkers to detect rejection or complications sooner to allow early medical intervention.

Islet Cell Transplants:  Here only the insulin-producing islet cells from the pancreas are transplanted. It minimizes the surgical complexity and potential complications.

Blood Glucose Monitoring: Continuous glucose monitoring (CGM) systems and advanced insulin pumps have become more precise and reliable. They help to manage blood glucose levels before and after transplantation.

Regenerative Medicine: Stem cell therapy and the development of insulin-producing beta cells from stem cells holds promise for future treatments.

FAQs

Free vector tiny people sitting and standing near giant faq

Q1: How long does a pancreas transplant for Type 1 Diabetes last?  

The lifespan of a transplanted pancreas can vary, but it may function effectively for several years or even decades in some cases.

Q2: Is pancreas transplantation a common procedure for Type 1 Diabetes?  

No, it is relatively rare due to the strict eligibility criteria and the availability of alternative treatments like insulin therapy.

Q3:Are there age restrictions for receiving a pancreas transplant for Type 1 Diabetes? 

Age is a factor in eligibility, and candidates are typically evaluated on a case-by-case basis, but it is less common in older individuals.

Q4: Can a living donor provide a pancreas for transplantation? 

Pancreas transplants are typically performed with deceased donor organs, not from living donors.

Q5: What is the cost of a pancreas transplant for Type 1 Diabetes? 

The cost can vary widely depending on factors like location, insurance coverage, and the need for additional procedures. It is usually a significant financial commitment.

Q6: What are the main lifestyle changes needed after a pancreas transplant? Recipients must adhere to a strict medication regimen and attend regular medical appointments. They also need to adopt a healthy lifestyle, including a balanced diet and regular exercise.

Q7: Are there any dietary restrictions after a pancreas transplant? 

Initially, dietary restrictions are common, but they may become less strict over time. It's important to work with a dietitian to ensure a healthy post-transplant diet.

Q8: Can a person with Type 1 Diabetes have a pancreas transplant if they have other medical conditions? 

It depends on the specific medical conditions and their severity. Each case is evaluated individually to determine eligibility for transplantation.
 

References:

https://www.who.int/news-room/fact-sheets/detail/diabetes

https://www.myshortlister.com/insights/diabetes-statistics

Related Blogs

Blog Banner Image

Dr. Samrat Jankar- Gastroenterologist and Laparoscopic Surgeon

MBBS, MS, FMAS and DNB (surgical gastroenterology) Surgical Gastroenterologist, Advanced Laparoscopic Surgeon, Abdominal Wall Reconstruction Surgeon 8+ years of rich experience

Blog Banner Image

10 Best Gastroenterologist in the World- Updated 2023

Explore world-class gastroenterologists renowned for their expertise, compassion, and innovative treatments. Experience comprehensive care for digestive health and well-being wherever you are in the world.

Blog Banner Image

New Ulcerative Colitis Treatment: FDA Approval 2022

Discover breakthroughs in ulcerative colitis treatment for adults. Explore new therapies offering hope for symptom relief and improved quality of life. Learn more now!

Blog Banner Image

Dupixent for EOE: Effective Treatment Solutions

Explore the potential of Dupixent for EoE treatment. Learn about its off-label use, effectiveness, and considerations with expert medical guidance.

Blog Banner Image

New Treatment for Gallbladder Cancer- FDA Approved

Unlock hope with new treatments for gallbladder cancer. Explore innovative therapies offering promise for improved outcomes. Learn more now!

Blog Banner Image

New Treatment for Peptic Ulcer- FDA Approved

Understanding peptic ulcers: Causes, symptoms, and effective treatments for relief and improved digestive health. Learn more today!

Blog Banner Image

New Treatment Options for Stomach Infections: Advancements

Explore cutting-edge treatment options for stomach infections. Discover new therapies offering hope for relief and improved digestive health. Learn more today!

Blog Banner Image

Can you have Bile Duct Obstruction after Gallbladder Removal?

Manage bile duct obstruction post-gallbladder removal. Expert care, innovative solutions. Restore comfort, find trusted clinics today!

Question and Answers

মুখ দিয়ে কফের মত প্রায় উঠছে খাবার পর হজম হচ্ছে না ঠিক ভাবে গ্যাস এর বরি হজমের টনিক খেয়েও ঠিক পুরোপুরি হচ্ছে না,রোগা হয়ে যাচ্ছি এটা কি ভিটামিনের অভাবে হতে পারে বা কিভাবে ভালো হবো বলে দিলে ভালো হতো ।

Female | 22

The signs you mentioned suggest you are experiencing gastric distress, which happens when the stomach can't process food properly. This often leads to gas buildup and causes discomfort. It's not related to a lack of vitamins. Try eating smaller portions, avoid spicy and oily foods, and chew your food slowly. Drinking a glass of warm water can also help you feel better.

Answered on 30th Sept '24

Dr. Samrat Jankar

Dr. Samrat Jankar

I'm hvg brown bleeding just 1 drop yesterday and 1 drop 2day I don't know y it's happened rather thn that yesterday i was hvg epigastric pain with stomach pain but 2day I'm hvg only epigastric pain

Female | 38

Are you experiencing brown bleeding and pain in your belly area? Brown bleeding might be due to the stomach or to some place in the digestive system. The pain in the epigastric region you are having could be due to your stomach. Try eating small, frequent meals and avoid spicy or greasy foods. If the bleeding persists or the pain gets worse, it is recommended that you see a healthcare provider for further advice.

Answered on 1st Oct '24

Dr. Samrat Jankar

Dr. Samrat Jankar

Gastroenterologyy Hospitals In Other Cities

Top Related Speciality Doctors In Other Cities

Cost Of Related Treatments In Country

Consult