Hello Tulakar, The traditional methods to treat stage IV melanoma are surgery, radiation therapy, and chemotherapy. Skin tumors or enlarged lymph nodes can be removed by surgery or treated with radiation therapy. Newer methods of treatment for stage IV melanoma are immunotherapy and targeted therapy. These treatments specifically target and destroy the cancer cells, avoiding damage to surrounding healthy cells and have promising results. Kindly consult an oncologist for clinical assessment and then plan treatment action, you can refer our page to find experts who will give additional information - Best Oncologist In India. Hope our answer helps you.